Magnetic behaviour of non‐interacting colloidal iron oxide nanoparticles in physiological solutions

Haracz, S.; Mróz, B.; Rybka, Jakub Dalibor; Giersig, Michael

doi:10.1002/crat.201500091

Cited by 8 publications

(8 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Magnetite nanoparticles can be synthesized using various methods, such as ultrasound irradiation [41], sol-gel transformation [42], thermal decomposition [43, 44], or co-precipitation [38]. The most commonly used methods are the last two.…”

Section: Resultsmentioning

confidence: 99%

Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications

et al. 2019

View full text Add to dashboard Cite

Bioengineered spider silk is a biomaterial that has exquisite mechanical properties, biocompatibility, and biodegradability. Iron oxide nanoparticles can be applied for the detection and analysis of biomolecules, target drug delivery, as MRI contrast agents and as therapeutic agents for hyperthermia-based cancer treatments. In this study, we investigated three bioengineered silks, MS1, MS2 and EMS2, and their potential to form a composite material with magnetic iron oxide nanoparticles (IONPs). The presence of IONPs did not impede the self-assembly properties of MS1, MS2, and EMS2 silks, and spheres formed. The EMS2 spheres had the highest content of IONPs, and the presence of magnetite IONPs in these carriers was confirmed by several methods such as SEM, EDXS, SQUID, MIP-OES and zeta potential measurement. The interaction of EMS2 and IONPs did not modify the superparamagnetic properties of the IONPs, but it influenced the secondary structure of the spheres. The composite particles exhibited a more than two-fold higher loading efficiency for doxorubicin than the plain EMS2 spheres. For both the EMS2 and EMS2/IONP spheres, the drug revealed a pH-dependent release profile with advantageous kinetics for carriers made of the composite material. The composite spheres can be potentially applied for a combined cancer treatment via hyperthermia and drug delivery.

show abstract

Section: Resultsmentioning

confidence: 99%

Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications

et al. 2019

View full text Add to dashboard Cite

show abstract

“…The most promising possibilities of nanoparticles are their use in biomedical applications. [1][2][3][4][5][6] Such potential applications include the use of magnetic nanoparticles (MNPs) in nuclear magnetic resonance (NMR) imaging (MRI), 7 cancer therapy (hyperthermia), 8 cancer diagnostics, 9 and gene therapy as well as components of drug-delivery systems. 10,11 Therefore, it is important to estimate the cytotoxicity of nanoparticles, which determines the potential medical applications of MNPs.…”

Section: Introductionmentioning

confidence: 99%

Interactions between magnetic nanoparticles and model lipid bilayers—Fourier transformed infrared spectroscopy (FTIR) studies of the molecular basis of nanotoxicity

Kręcisz

Rybka

Strugała

et al. 2016

Journal of Applied Physics

Self Cite

View full text Add to dashboard Cite

The toxicity of nanoparticles (nanotoxicity) is often associated with their interruption of biological membranes. The effect of polymer-coated magnetic nanoparticles (with different Fe 3 O 4 core sizes and different polymeric coatings) on a model biological membrane system of vesicles formed by dimyristoylphosphatidylcholine (DMPC) was studied. Selected magnetic nanoparticles with core sizes ranging from 3 to 13 nm (in diameter) were characterised by transmission electron microscopy. Samples with 10% DMPC and different nanoparticle concentrations were studied by attenuated total reflectance-Fourier transform infrared spectroscopy to establish the influence of nanoparticles on the phase behaviour of model phospholipid systems. Published by AIP Publishing.

show abstract

“…These are widely investigated due to their potential of interacting properties in biomedical applications, such as drug delivery, cell separation, genetic engineering etc. (Haracz et al 2015). Therefore, study of interacting drops may help in understanding their applications in these fields.…”

Section: Background and Motivationmentioning

confidence: 99%

Salt crystal growth in interacting drops of a complex biopolymer: Statistical characterization using FESEM images

Choudhury

Das

Roy

et al. 2019

Chemical Engineering Science

View full text Add to dashboard Cite

A simple colloidal drop generally forms ring like patterns after drying. The deposition morphology of the dried drop changes significantly when such a drop dries in the vicinity of another similar drop.Here we present an observational study and statistical analysis of the patterns formed inside an isolated as well as interacting drops of gelatin containing sodium sulfate (Na2SO4). In all the cases, multiple concentric regions of solute particles combined with the polymer gel appear as the drops dry up. Needle crystals of sulfur and coacervates of salt and gelatin are visible in some regions. The outer region becomes non-uniform, so does the size distribution of the needle crystals and coacervates. The non-uniformity increases with proximity of the drops. Here we propose a novel mechanism of growing patterns inside the single drop during drying and correlate that with the results obtained for interacting drops. This study and the proposed mechanism provide insights into the future studies of drying drops under different physical conditions. Further we explore the statistical characteristics of the single and interacting drops using the field emission scanning electron microscopy (FESEM) images. Next, we report fractal and image texture analyses along with object shape statistics of the drop FESEM images, under various experimental conditions. Several statistical hypothesis tests have been carried out to identify the most significant features.

show abstract

Magnetic behaviour of non‐interacting colloidal iron oxide nanoparticles in physiological solutions

Cited by 8 publications

References 24 publications

Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications

Composite spheres made of bioengineered spider silk and iron oxide nanoparticles for theranostics applications

Interactions between magnetic nanoparticles and model lipid bilayers—Fourier transformed infrared spectroscopy (FTIR) studies of the molecular basis of nanotoxicity

Salt crystal growth in interacting drops of a complex biopolymer: Statistical characterization using FESEM images

Contact Info

Product

Resources

About