Magnetic classification in health sciences and in chemical engineering

Augusto, Paulo A.; Castelo-Grande, Teresa; Augusto, Pedro

doi:10.1016/j.cej.2005.02.013

Cited by 26 publications

(8 citation statements)

References 18 publications

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“…Several magnetic separation devices have demonstrated the separation of magnetic particles in a microfluidic channel utilizing an external permanent magnet [5][6][7], integrated magnetic posts [8,9], or an integrated microelectromagnet [10,11]. However, these devices and/or processes still have a major drawback, which is the capture of the magnetic particles occurs only at the wall of channels/tubes in a static trapping mode.…”

Section: Introductionmentioning

confidence: 99%

Magnetic-based purification system with simultaneous sample washing and concentration

Ramadan

Lau

2009

Anal Bioanal Chem

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Simultaneous washing and concentration of magnetic microparticles was demonstrated using a rotational magnetic system under a continuous-flow condition. The rotation of periodically arranged permanent magnets close to a fluidic channel carrying a suspension of magnetic particles allows the trapping and releasing of particles along the fluidic channel in a periodic manner. Each trapping and releasing event resembles one washing cycle in conventional biological assays. Concentration efficiencies of 99.75 +/- 0.083% at a flow rate of 200 microl/min and 88.10 +/- 3.17% at a flow rate of 1,000 microl/min and a purification efficiency of 99.10 +/- 4.3% at a flow rate of 900 microl/min were achieved.

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Section: Introductionmentioning

confidence: 99%

Magnetic-based purification system with simultaneous sample washing and concentration

Ramadan

Lau

2009

Anal Bioanal Chem

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“…For the applications in sight (adsorption, Fenton reaction, catalysis, etc.) [11,27] the main characteristics of the chosen process must be: easiness of synthesis; low-cost particles; easiness of processing; easiness of scale-up; production of large quantities of particles; high flow throughputs; and monodispersity is not a requirement. Considering these factors and the information on Table 1, the choice fell on the co-precipitation method.…”

Section: Process Selectionmentioning

confidence: 99%

“…For the applications in sight (drug delivery, magnetic hyperthermia, etc.) [27,34,35] the main characteristics of the chosen process must be: easiness of synthesis; monodispersity; easiness to scale-up; production of moderate quantities; low flow-throughputs; good shape control and crystallinity and low nanosizes (particles should behave supermagnetically). Considering these factors and Table 1, the choice fell on the hydrothermal method.…”

Section: Biotechnological Applicationsmentioning

confidence: 99%

Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use

et al. 2020

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Very few economical and process engineering studies have been made concerning the scale-up and implementation of nanomagnetic particle manufacturing into a full-scale plant, and determination of its viability. In this work we describe such a study for two types of industrial plants, one for manufacturing magnetic particles for applications in the environmental area, and the other for manufacturing nanomagnetic particles for applications in the biotechnology area; the two different applications are compared. The following methodology was followed: establish the manufacturing process for each application; determine the market demand of the product (magnetic nanoparticles) for both applications; determine the production capacity of each plant; engineer all the manufacturing process, determining all the process units and performing all the mass and energy balances for both plants; scale-up the main equipment; and determine the global economic impact and profitability. At the end both plants are found to be technologically and economically viable, the characteristics of the final products being, however, quite different, as well as the process engineering, economic analysis, and scale-up.

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“…The large majority of environmental applications [16][17][18] are usually concerned with the removal of contaminants/nutrients from water/wastewaters using nanomagnetic particles as sorption vehicles [19][20][21][22][23][24][25] that are at the end magnetically separated (containing the respective contaminant/nutrient) from the watery effluent and then recycled and reused. Another environmental added over 10 min and, where appropriate, the surfactant was added.…”

Section: Introductionmentioning

confidence: 99%

Water Decontamination with Magnetic Particles by Adsorption and Chemical Degradation. Influence of the Manufacturing Parameters

et al. 2020

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Many different processes for manufacturing of magnetic particles are present in scientific literature. However, the large majority are not able to be applied to large-scale real operations. In this study, we present an experiment undertaken to determine advisable values and options for the main variables and factors for the application of the reverse co-precipitation method to produce magnetic particles for real environmental applications. In such, we have tried a conjugation of values/factors that has led to 12 main experiments and production of 12 different particles. After an initial study concerning their main characteristics, these 12 different particles were applied for the sorption removal of COD from real wastewater samples (efficiencies between 70% and 81%) and degradation of Methylene blue by Fenton reaction (degradation efficiencies up to 100%). The main conclusion from this work is that the best set of values depends on the target environmental application, and this set of values were determined for the two applications studied.

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Magnetic classification in health sciences and in chemical engineering

Cited by 26 publications

References 18 publications

Magnetic-based purification system with simultaneous sample washing and concentration

Magnetic-based purification system with simultaneous sample washing and concentration

Upscale Design, Process Development, and Economic Analysis of Industrial Plants for Nanomagnetic Particle Production for Environmental and Biomedical Use

Water Decontamination with Magnetic Particles by Adsorption and Chemical Degradation. Influence of the Manufacturing Parameters

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