“…The peaks of 3449 and 3346 cm −1 can be attributed to the stretching vibration of O–H group of nasturtium (plant) phenolic compounds. It was revealed that phenolic compounds of plants played a reducing role for the synthesis of metal NPs 110 . Figure 2 FT-IR spectra of Zn-doped CuFe 2 O 4 NPs.…”
Zn-doped CuFe2O4 nanoparticles (NPs) were eco-friendly synthesized using plant extract. These nanoparticles were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy and thermal gravimetric analysis (TGA). SEM image showed spherical NPs with size range less than 30 nm. In the EDS diagram, the elements of zinc, copper, iron, and oxygen are shown. The cytotoxicity and anticancer properties of Zn-doped CuFe2O4 NPs were evaluated on macrophage normal cells and A549 lung cancer cells. The cytotoxic effects of Zn-doped CuFe2O4 and CuFe2O4 NPs on A549 cancer cell lines were analyzed. The Zn-doped CuFe2O4 and CuFe2O4 NPs demonstrated IC50 values 95.8 and 278.4 µg/mL on A549 cancer cell, respectively. Additionally, Zn-doped CuFe2O4 and CuFe2O4 NPs had IC80 values of 8.31 and 16.1 µg/mL on A549 cancer cell, respectively. Notably, doping Zn on CuFe2O4 NPs displayed better cytotoxic effects on A549 cancer cells compared with the CuFe2O4 NPs alone. Also spinel nanocrystals of Zn-doped CuFe2O4 (~ 13 nm) had a minimum toxicity (CC50 = 136.6 µg/mL) on macrophages J774 Cell Line.
“…The peaks of 3449 and 3346 cm −1 can be attributed to the stretching vibration of O–H group of nasturtium (plant) phenolic compounds. It was revealed that phenolic compounds of plants played a reducing role for the synthesis of metal NPs 110 . Figure 2 FT-IR spectra of Zn-doped CuFe 2 O 4 NPs.…”
Zn-doped CuFe2O4 nanoparticles (NPs) were eco-friendly synthesized using plant extract. These nanoparticles were characterized by X-ray diffraction, Fourier-transform infrared spectroscopy, scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy and thermal gravimetric analysis (TGA). SEM image showed spherical NPs with size range less than 30 nm. In the EDS diagram, the elements of zinc, copper, iron, and oxygen are shown. The cytotoxicity and anticancer properties of Zn-doped CuFe2O4 NPs were evaluated on macrophage normal cells and A549 lung cancer cells. The cytotoxic effects of Zn-doped CuFe2O4 and CuFe2O4 NPs on A549 cancer cell lines were analyzed. The Zn-doped CuFe2O4 and CuFe2O4 NPs demonstrated IC50 values 95.8 and 278.4 µg/mL on A549 cancer cell, respectively. Additionally, Zn-doped CuFe2O4 and CuFe2O4 NPs had IC80 values of 8.31 and 16.1 µg/mL on A549 cancer cell, respectively. Notably, doping Zn on CuFe2O4 NPs displayed better cytotoxic effects on A549 cancer cells compared with the CuFe2O4 NPs alone. Also spinel nanocrystals of Zn-doped CuFe2O4 (~ 13 nm) had a minimum toxicity (CC50 = 136.6 µg/mL) on macrophages J774 Cell Line.
“…The peaks of 3449 and 3346 cm − 1 can be attributed to the stretching vibration of O-H group of nasturtium phenolic compounds. It was revealed that phenolic compounds of plants played a reducing role for the synthesis of metal NPs [17]. Changes in the physical behavior of Zn-doped CuFe 2 O 4 NPs were evaluated using TGA and derivative thermal gravimetric (DTG) analysis based on temperature and time using TG 209 F3Tarsus®, NETZSCH Germany Company device (Fig.…”
Zn-doped ceramic CuFe2O4 nanoparticles were eco-friendly synthesized using plant extract at room temperature. These nanoparticles were characterized by X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), energy-dispersive X-ray spectroscopy (EDX), thermal gravimetric analysis (TGA), and transmission electron microscopy (TEM). As a result, spinal crystallites of Zn-doped CuFe2O4 (~ 13 nm) had a minimum toxicity (CC50 = 136.6 µg/ml) on macrophages J774 Cell Line.
“…Similarly, Kiani et al synthesized cobalt oxide nanoparticles through the reaction of typical Spanish sage and cobalt nitrate [37]. Moreover, Raeisi et al synthesized cobalt oxide nanoparticles by plant extracts from fresh leaves of rosemary twigs [38]. Phytochemicals in the extract of Rhamnus virgata leaf also have the functions to act as reducing and stabilizing agents, which can thus be applied to produce cobalt oxide nanoparticles [18].…”
Cobalt is essential to the metabolism of all animals due to its key role in cobalamin, also known as vitamin B12, the primary biological reservoir of cobalt as an ultra-trace element. Current cancer treatment strategies, including chemotherapy and radiotherapy, have been seriously restricted by their side effects and low efficiency for a long time, which urges us to develop new technologies for more effective and much safer anticancer therapies. Novel nanotechnologies, based on different kinds of functional nanomaterials, have been proved to act as effective and promising strategies for anticancer treatment. Based on the important biological roles of cobalt, cobalt oxide nanoparticles (NPs) have been widely developed for their attractive biomedical applications, especially their potential for anticancer treatments due to their selective inhibition of cancer cells. Thus, more and more attention has been attracted to the preparation, characterization and anticancer investigation of cobalt oxide nanoparticles in recent years, which is expected to introduce novel anticancer treatment strategies. In this review, we summarize the synthesis methods of cobalt oxide nanoparticles to discuss the advantages and restrictions for their preparation. Moreover, we emphatically discuss the anticancer functions of cobalt oxide nanoparticles as well as their underlying mechanisms to promote the development of cobalt oxide nanoparticles for anticancer treatments, which might finally benefit the current anticancer therapeutics based on functional cobalt oxide nanoparticles.
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