Magnetic nanocrystallites strontium hexaferrite as an efficient catalyst in the green Betti reaction

Ziarani, Ghodsi Mohammadi; Asl, Zhila Kazemi; Gholamzadeh, Parisa; Badiei, Alireza; Afshar, Morteza

doi:10.1080/24701556.2019.1574816

Cited by 6 publications

(1 citation statement)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To facilitate the conversion smoothly, high temperature, [21] microwave [13,16b,22] and ultrasonic irradiation are typical strategies in combination with certain catalysts (Scheme 2b). In recent studies, many highly efficient catalysts with good stability and reusability such as clay, [23] activated Fuller's earth, [24] functionalized ionic liquid (3‐( N , N ‐dimethyldodecylammonium)propanesulfonic acid hydrogen sulfate), [25] porous carbon spheres (doped by nitrogen and sulfur, and ferric hydrogen sulfate), [26] and nanocatalysts (modified graphene oxide gold nanoparticles [27] and magnetic nanocrystallites strontium hexaferrite [28] ) (Scheme 2c) have been developed. However, in most cases, it usually took a long time for reaction completion under the assistance of catalysts at moderate to high temperatures.…”

Section: Introductionmentioning

confidence: 99%

Catalyst‐Free Accelerated Three‐Component Synthesis of Betti Bases in Microdroplets

Jin

Dai

et al. 2022

ChemPlusChem

View full text Add to dashboard Cite

Due to their important roles in medicine and asymmetric metal catalysis, the formation of Betti bases has attracted wide interest in organic chemical community. Traditional multicomponent reaction methods for synthesizing Betti bases normally require long reaction times under harsh conditions (high temperature, microwave or ultrasonic irradiation, etc.) in the presence of various catalysts. In this study, we developed a mild, highly efficient and environmentally friendly method to synthesize Betti bases without the use of any catalysts in microdroplets. The Betti reaction was accelerated by 6.53×103 in microdroplets by comparing the measured rate constant in bulk. Fifteen Betti bases were synthesized by the microdroplet method using a variety of aldehydes, naphthols and amines with 68–98 % yields at a scaled‐up amount of 1.9 g h−1. Overall it is an attractive alternative to classic organic synthesis for the construction of Betti bases and derivatives.

show abstract