Magnetic nanoparticle-supported glutathione: a conceptually sustainable organocatalyst

Abstract

A conceptually novel nanoparticle-supported and magnetically recoverable organocatalyst has been developed, which is readily prepared from inexpensive starting materials in a truly sustainable manner; which catalyzes the Paal-Knorr reaction with high yield in pure aqueous medium that avoids the use of toxic organic solvents, even in the workup step.

Magnetically Separable Base Catalysts: Heterogeneous Catalysis vs. Quasi-Homogeneous Catalysis

“…The supported catalysts proved to be effective and easily separated from the reaction media by applying an external magnetic field. Moreover, the ability of magnetic nanoparticles to serve efficiently as nano-support for organocatalytic systems has been recently reported [22][23][24][25][26][27][28][29][30][31][32]. We have described the highly selective hydroformylation reaction using rhodium catalysts supported on dendronized magnetic nanoparticles [33].…”

Nano-catalysts with magnetic core: sustainable options for greener synthesis

“…The use of MNPs as catalysts in chemical synthesis has been extensively studied in recent years as the recovery of expensive catalysts after their use are some of the salient features in the sustainable process development [17][18][19][20][21]. MNPs coated with benign ligands such as dopamine or glutathione have also been developed and used as heterogeneous catalysts for numerous organic transformations and syntheses [17][18][19][20][21].…”

“…MNPs coated with benign ligands such as dopamine or glutathione have also been developed and used as heterogeneous catalysts for numerous organic transformations and syntheses [17][18][19][20][21]. The functionalization of the surfaces of nano-sized magnetic materials provides a quasi-homogeneous phase in reaction media and acts as a bridge between heterogeneous and homogeneous catalysis thus retaining the relative virtues of both of the systems.…”

Nano Nickel-Cobalt Ferrite Catalyzed One Pot Synthesis of 14-Aryl-14H-Dibenzo[A, J]Xanthenes and 12-Aryl-8, 9, 10, 12-Tetrahydrobenzo[A]Xanthene-11-One Derivatives

“…The greener generation of nanoparticles and their eco-friendly applications in catalysis via magnetically recoverable and recyclable nano-catalysts for a variety of oxidation, reduction, and condensation reactions [37][38][39][40] , has made an incredible impact on the development of sustainable pathways. Magnetically recyclable nano catalysts and their use in benign media is an ideal merge for the development of sustainable methodologies in organic synthesis.…”