Magnetic Nanoparticles Based Solid Phase Extraction Methods for the Determination of Trace Elements

Er, Elif Öztürk; Bozyiğit, Gamze Dalgıç; Büyükpınar, Çağdaş; Bakırdere, Sezgin

doi:10.1080/10408347.2020.1797465

Cited by 60 publications

(27 citation statements)

References 202 publications

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“…Metallic nanoparticles (MNPs) have found varying applications on an industrial scale, this boom has also affected the area of analytical chemistry. MNPs are now heavily utilized in many extraction procedures for the separation/pre-concentration of organic (Sajid et al, 2021 ; Wu et al, 2021 ) and inorganic (Filik and Avan, 2019 ; Er et al, 2020 ) analytes from environmental, biological, pharmaceutical, and food samples. However, the application of MNPs in column experiments is rather rare, probably due to their tendency to form agglomerates (Karadjova et al, 2016 ; Hashemi et al, 2018 ).…”

Section: Discussionmentioning

confidence: 99%

Application of Metallic Nanoparticles and Their Hybrids as Innovative Sorbents for Separation and Pre-concentration of Trace Elements by Dispersive Micro-Solid Phase Extraction: A Minireview

Hagarová

Nemček

2021

Front. Chem.

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It is indisputable that separation techniques have found their rightful place in current analytical chemistry, considering the growing complexity of analyzed samples and (ultra)trace concentration levels of many studied analytes. Among separation techniques, extraction is one of the most popular ones due to its efficiency, simplicity, low cost and short processing times. Nonetheless, research interests are directed toward the enhancement of performance of these procedures in terms of selectivity. Dispersive solid phase extraction (DSPE) represents a novel alternative to conventional solid phase extraction (SPE) which not only delivers environment-friendly extraction with less solvent consumption, but also significantly improves analytical figures of merit. A miniaturized modification of DSPE, known as dispersive micro-solid phase extraction (DMSPE), is one of the most recent trends and can be applied for the extraction of wide variety of analytes from various liquid matrices. While DSPE procedures generally use sorbents of different origin and sizes, in DMSPE predominantly nanostructured materials are required. The aim of this paper is to provide an overview of recently published original papers on DMSPE procedures in which metallic nanoparticles and hybrid materials containing metallic particles along with other (often carbon-based) constituent(s) at the nanometer level have been utilized for separation and pre-concentration of (ultra)trace elements in liquid samples. The studies included in this review emphasize the great analytical potential of procedures producing reliable results in the analysis of complex liquid matrices, where the detection of target analyte is often complicated by the presence of interfering substances.

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Section: Discussionmentioning

confidence: 99%

Application of Metallic Nanoparticles and Their Hybrids as Innovative Sorbents for Separation and Pre-concentration of Trace Elements by Dispersive Micro-Solid Phase Extraction: A Minireview

Hagarová

Nemček

2021

Front. Chem.

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“…The benefit of this approach is its ability to attain a large number of particles in an individual batch. The drawback is its lack of control over the particle’s shape and size, which is an important aspect to biomedical applications [ 48 ]. The “bottom-up” approach could begin with either a ferrous (Fe 2+ ) or Ferric (Fe 3+ ) ion salt.…”

Section: Methodsmentioning

confidence: 99%

Emerging Application of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer

2021

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Cancer is a disease that has resulted in millions of deaths worldwide. The current conventional therapies utilized for the treatment of cancer have detrimental side effects. This led scientific researchers to explore new therapeutic avenues with an improved benefit to risk profile. Researchers have found nanoparticles, particles between the 1 and 100 nm range, to be encouraging tools in the area of cancer. Magnetic nanoparticles are one of many available nanoparticles at present. Magnetic nanoparticles have increasingly been receiving a considerable amount of attention in recent years owing to their unique magnetic properties, among many others. Magnetic nanoparticles can be controlled by an external magnetic field, signifying their ability to be site specific. The most popular approaches for the synthesis of magnetic nanoparticles are co-precipitation, thermal decomposition, hydrothermal, and polyol synthesis. The functionalization of magnetic nanoparticles is essential as it significantly increases their biocompatibility. The most utilized functionalization agents are comprised of polymers. The synthesis and functionalization of magnetic nanoparticles will be further explored in this review. The biomedical applications of magnetic nanoparticles investigated in this review are drug delivery, magnetic hyperthermia, and diagnosis. The diagnosis aspect focuses on the utilization of magnetic nanoparticles as contrast agents in magnetic resonance imaging. Clinical trials and toxicology studies relating to the application of magnetic nanoparticles for the diagnosis and treatment of cancer will also be discussed in this review.

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“…“top‐down” method involves with high energy ball milling process of a magnetic sample until the desired nanoscale size is achieved. [ 18 ] The advantage of “top‐down” method is, high number of particles can be achieved in a single batch while the disadvantage is the control over particle shape and size is compromised which is important in biomedical application. [ 18 ] “Bottom‐up” method depends on starting with a salt of ferrous (Fe 2+ ) or Ferric (Fe 3+ ) ion and undergoing a different chemical process to nucleate and induce seeded growth to grow particles to the desired hydrodynamic diameter.…”

Section: Synthesis Of Mnpsmentioning

confidence: 99%

Recent progress of magnetic nanoparticles in biomedical applications: A review

et al. 2021

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Magnetic nanoparticles (MNPs) offer tremendous potentialities in biomedical applications for a long while. Since these materials' interactions in biological media largely rely on their crystal structures, sizes, and shapes, detailed studies on their synthesis mechanism for medicinal aspects are crucial. Despite many review reports that have already been published on MNPs, they mainly have focused either on their perspective in biomedical applications or their synthesis and characterization along with functionalization mechanisms as individual entities. For this reason, this review uncovers a comprehensive insight into the ongoing improvement of fabrication processes, surface functionalization of MNPs for biomedical applications together. Besides, various magnetic nanocomposite (MNCs) for smart drug delivery, recent hyperthermia treatment, lab‐on‐a‐chip, and magnetic bio‐separation, and some of the recent emerging imaging techniques using MNPs are discussed. A detailed analysis of toxicity, challenges, and recent progress of clinical trials of MNPs is sketched out to open numerous entryways for advanced research on MNPs for biomedical applications.

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Magnetic Nanoparticles Based Solid Phase Extraction Methods for the Determination of Trace Elements

Cited by 60 publications

References 202 publications

Application of Metallic Nanoparticles and Their Hybrids as Innovative Sorbents for Separation and Pre-concentration of Trace Elements by Dispersive Micro-Solid Phase Extraction: A Minireview

Application of Metallic Nanoparticles and Their Hybrids as Innovative Sorbents for Separation and Pre-concentration of Trace Elements by Dispersive Micro-Solid Phase Extraction: A Minireview

Emerging Application of Magnetic Nanoparticles for Diagnosis and Treatment of Cancer

Recent progress of magnetic nanoparticles in biomedical applications: A review

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