Magnetic nanoparticles fabricated/integrated with microfluidics for biological applications: A review

Toudeshkchouei, Mahtab Ghasemi; Abdoos, Hassan

doi:10.1007/s10544-023-00693-9

Biomed Microdevices

2024

DOI: 10.1007/s10544-023-00693-9

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Magnetic nanoparticles fabricated/integrated with microfluidics for biological applications: A review

Mahtab Ghasemi Toudeshkchouei,

Hassan Abdoos

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2024

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Cited by 3 publications

References 92 publications

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Generation, manipulation, detection and biomedical applications of magnetic droplets in microfluidic chips

Xu,

Shi,

Tan

et al. 2024

Analyst

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Generation, manipulation, detection and biomedical applications of magnetic droplets in microfluidic chips

Xu,

Shi,

Tan

et al. 2024

Analyst

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Effect of divalent ion of strontium substitution on the structural, optical, magnetic and blood compatibility studies in cobalt ferrite

Ergin,

Özçelik,

İçin

et al. 2024

Phys. Scr.

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This study investigates the effects of Sr2+ substitution on the structural, morphological, and magnetic properties of magnetic cobalt ferrite (CoFe2O4). Through sol-gel auto-combustion synthesis, Sr2+ was substituted into Co-spinel ferrites (Co1 xSrxFe2O4, where x=0.0, 0.25, 0.5, 0.75, 1.0). SEM analysis revealed spherical grains with an average size of 54.4 nm. XRD analysis indicated systematic changes in crystallographic parameters and the formation of secondary phases with Sr-substitution. While the crystal size for CoFe2O4 was calculated as 262 nm, this value was determined as 18 nm for Co0.25Sr0.75Fe2O4. FT-IR results suggested increased force constants of octahedral and tetrahedral bonds with higher Sr content, with main vibration bands at 423.6 and 606 cm-1. M-H curves exhibited S-shaped behavior, indicating drastic magnetic property changes with Sr2+ substitution. Coercivity field (Hc), saturation magnetization (MS), and remanent magnetization (Mr) values ranged from 1447.8-545.4 Oe, 58.8-14 emu/g, and 36.8-7.6 emu/g, respectively. Blood compatibility experiments highlighted Co0.75Sr0.25Fe2O4 nanoparticles with significantly low hemolysis rates compared to other concentrations.

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Magnetic particles–integrated microfluidics: from physical mechanisms to biological applications

Paryab,

Saghatchi,

Zarin

et al. 2024

Reviews in Chemical Engineering

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Magnetic nanoparticles (MNPs) have garnered significant attention in biomedical applications. Due to their large surface area and tunable properties, MNPs are used in microfluidic systems, which allow for the manipulation and control of fluids at micro- or nanoscale. Using microfluidic systems allows for a faster, less expensive, and more efficient approach to applications like bioanalysis. MNPs in microfluidics can precisely identify and detect bioanalytes on a single chip by controlling analytes in conjunction with magnetic particles (MPs) and separating various particles for analytical functions at the micro- and nanoscales. Numerous uses for these instruments, including cell-based research, proteomics, and diagnostics, have been reported. The successful reduction in the size of analytical assays and the creation of compact LOC platforms have been made possible with the assistance of microfluidics. Microfluidics is a highly effective method for manipulating fluids as a continuous flow or discrete droplets. Since the implementation of the LOC technology, various microfluidic methods have been developed to improve the efficiency and precision of sorting, separating, or isolating cells or microparticles from their original samples. These techniques aim to surpass traditional laboratory procedures. This review focuses on the recent progress in utilizing microfluidic systems that incorporate MNPs for biological applications.

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Magnetic nanoparticles fabricated/integrated with microfluidics for biological applications: A review

Cited by 3 publications

References 92 publications

Generation, manipulation, detection and biomedical applications of magnetic droplets in microfluidic chips

Generation, manipulation, detection and biomedical applications of magnetic droplets in microfluidic chips

Effect of divalent ion of strontium substitution on the structural, optical, magnetic and blood compatibility studies in cobalt ferrite

Magnetic particles–integrated microfluidics: from physical mechanisms to biological applications

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