Magnetic Properties of Encapsulated Magnetite in PLGA Nanospheres

Koneracká, M.; Závišová, V.; Τimko, M.; Kopčanský, P.; Tomašovičová, Natália; Csach, К.

doi:10.12693/aphyspola.113.595

Cited by 12 publications

(7 citation statements)

References 3 publications

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“…Two characteristics of FTIR spectra of hydrophilic nanoparticles are interesting to remark. First, we do not observe the presence of 11‐AATS; second, the FTIR spectra are in agreement with the literature for PEG‐ and DEXTRAN‐coated nanoparticles …”

Section: Resultssupporting

confidence: 90%

“…First, we do not observe the presence of 11-AATS; second, the FTIR spectra are in agreement with the literature for PEG-and DEXTRAN-coated nanoparticles. 38,39 SPA measurements Figure 4 shows the time dependence of the temperature of an aqueous-based ferrofluid containing our SPIONs with concentration of 0.5 wt % in the presence of an ac magnetic field with H 5 13 kA/m and f 5 250 kHz. We observed an increase of $3.2 C and 2.5 C in only 10 s for the DEXTRAN-and PEG-coated SPIONs, respectively.…”

Section: Ftir and Hydrodynamic Radiusmentioning

confidence: 99%

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In vitro and in vivo experiments with iron oxide nanoparticles functionalized with DEXTRAN or polyethylene glycol for medical applications: Magnetic targeting

et al. 2014

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In this research work, DEXTRAN- and polyethylene glycol (PEG)-coated iron-oxide superparamagnetic nanoparticles were synthetized and their cytotoxicity and biodistribution assessed. Well-crystalline hydrophobic Fe3 O4 SPIONs were formed by a thermal decomposition process with d = 18 nm and σ = 2 nm; finally, the character of SPIONs was changed to hydrophilic by a post-synthesis procedure with the functionalization of the SPIONs with PEG or DEXTRAN. The nanoparticles present high saturation magnetization and superparamagnetic behavior at room temperature, and the hydrodynamic diameters of DEXTRAN- and PEG-coated SPIONs were measured as 170 and 120 nm, respectively. PEG- and DEXTRAN-coated SPIONs have a Specific Power Absorption SPA of 320 and 400 W/g, respectively, in an ac magnetic field with amplitude of 13 kA/m and frequency of 256 kHz. In vitro studies using VERO and MDCK cell lineages were performed to study the cytotoxicity and cell uptake of the SPIONs. For both cell lineages, PEG- and DEXTRAN-coated nanoparticles presented high cell viability for concentrations as high as 200 μg/mL. In vivo studies were conducted using BALB/c mice inoculating the SPIONs intravenously and exposing them to the presence of an external magnet located over the tumour. It was observed that the amount of PEG-coated SPIONs in the tumor increased by up to 160% when using the external permanent magnetic as opposed to those animals that were not exposed to the external magnetic field.

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Section: Resultssupporting

confidence: 90%

Section: Ftir and Hydrodynamic Radiusmentioning

confidence: 99%

In vitro and in vivo experiments with iron oxide nanoparticles functionalized with DEXTRAN or polyethylene glycol for medical applications: Magnetic targeting

et al. 2014

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“…As determined by DLS measurements in water (Figure 2A), the average hydrodynamic diameter of these bicompartmental particles decreased to 602±200 nm after calcination. This is consistent with the shrinkage of particles during condensation and thermal treatment 29. Assuming the density of PLGA and titania to be 1.2 and 4 g/cm 3 , respectively, we estimated an average diameter reduction of 25%, which is in good agreement with the results of the TGA analysis.…”

Section: Methodssupporting

confidence: 88%

Anisotropic Janus Catalysts for Spatially Controlled Chemical Reactions

Lee

et al. 2012

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Bicompartmental composite nanoparticles are prepared by electryhydrodyanimic co‐jetting with an organic‐soluble polymer and titanium precursor, followed by a calcination step to convert the composite particles into stable Janus catalysts. The Janus catalysts retains the original shape and bicompartmental character. Selective growth of carbon nanotubes on one side of the nanoparticles is achieved by spatially localized iron oxide nanocrystals. The product is a new type of Janus particles.

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“…[12, 13, 21, 22] Herein, we demonstrated WBPLP-/BPLP-conjugated MNP structures of the DICT-NPs. Figure 1A shows schematic representation of WBPLP-MNPs and BPLP-MNPs.…”

mentioning

confidence: 99%

“…It was frequently observed that there was a decrease in saturation magnetization when MNPs were coated with various polymers such as polystyrene, [25] PNIPAAm, [12] PLGA, [21] and PEG. [22] The remanence of WBPLP-MNPs and BPLP-MNPs was 5.14 and 5.77 (M r M s −1 ), respectively, as compared to 6.73 (M r M s −1 ) in the case of bare MNPs. Whereas, the coercivity of WBPLP-MNPs and BPLP-MNPs was 50.59 and 59.72 Oe, respectively, as compared to 65.23 Oe in the case of bare MNPs (Supporting Information, Table S2).…”

mentioning

confidence: 99%