Bi-2212 cylindrical rods were obtained using a laser-induced directional solidification system. Although as-grown Bi-2212 samples are well textured, they do not exhibit superconducting behavior and, as a result, need further heat treatments. The modifications taking place during annealing were analyzed in the present work, in particular with respect to the evolution of the microstructure with the annealing time and the phase content. Diffusion processes in which the Bi-2212 phase grows along the thickness of the platelets take place during annealing. The presented results show that the physical properties of these samples improve during the initial approximately 60 h of annealing and that they remain constant thereafter.