Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient

Bottini, Peter B.; Carr, Albert A.; Lm, Prisant; Flickinger, Fred W.; Allison, J. B.; Gottdiener, John S.

doi:10.1016/0895-7061(94)00178-e

Cited by 320 publications

(220 citation statements)

References 34 publications

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“…Demonstration of LVM regression using echocardiographic methods also requires relatively large cohorts of patients because of the high observer and interstudy variability. 18,[22][23][24] Cardiac MRI has become the technique of choice for precise measurements of LVM. This 3D technique, with excellent definition of endocardial and epicardial borders, is highly reproducible, which means that a much smaller sample size is needed to detect LVM regression in clinical trials.…”

Section: Perspectivesmentioning

confidence: 99%

“…LVM, as measured by cardiac MRI, has been validated in animal studies 20,21 and has been demonstrated to be more accurate and reproducible than M-mode and 2D echocardiography measurements. 18,22,23 As a result of the superior accuracy and reproducibility, fewer subjects are needed in research studies using cardiac MRI. 24 The aim of our study was to evaluate the Sokolow-Lyon voltage, Cornell sex-specific voltage, Sokolow-Lyon product, and Cornell product criteria against LVM index as measured by cardiac MRI in a large cohort of patients.…”

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confidence: 99%

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New Gender-Specific Partition Values for ECG Criteria of Left Ventricular Hypertrophy

et al. 2004

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Abstract-ECG criteria for left ventricular hypertrophy (LVH) were mostly validated using left ventricular mass (LVM) as measured by M-mode echocardiography. LVM as measured by cardiac MRI has been demonstrated to be much more accurate and reproducible. We reevaluated the sensitivity and specificity of 4 ECG criteria of LVH against LVM as measured by cardiac MRI. Patients with systemic hypertension (nϭ288) and 60 normal volunteers had their LVM measured using a 1.5-Tesla MRI system. A 12-lead ECG was recorded, and 4 ECG criteria were evaluated: Sokolow-Lyon voltage, Cornell voltage, Cornell product, and Sokolow-Lyon product. Based on a cardiac MRI normal range, 39.9% of the hypertensive males and 36.7% of the hypertensive females had elevated LVM index. At a specificity of 95%, the Sokolow-Lyon product criterion had the highest sensitivity in females (26.2%), the Cornell criterion had the highest sensitivity in males (26.2%), and the Cornell product criteria had a relatively high sensitivity in both males and females (25.0% and 23.8%). Receiver operating characteristic curves showed the Cornell and Cornell product criteria to be superior for males whereas the Sokolow-Lyon product criterion was superior for females. Comparing the mean LVM index values of the subjects who were ECG LVH positive to the normal volunteers indicated that the ECG LVH criteria detect individuals with an LVM index substantially above the normal range. We have redefined the partition values for 4 different ECG LVH criteria, according to gender, and found that they detect subjects with markedly elevated LVM index.

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Section: Perspectivesmentioning

confidence: 99%

mentioning

confidence: 99%

New Gender-Specific Partition Values for ECG Criteria of Left Ventricular Hypertrophy

et al. 2004

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“…Although MRI appears to be more precise and reliable for measuring LVM, 45 it is limited by cost, fixed facilities and claustrophobia. The echocardiography widely used permits the realisation of largescale studies which can then include a representative population of hypertensive LVH patients.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design

et al. 2002

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The PICXEL study is designed to evaluate the effects of long-term administration of very low-dose combination perindopril 2 mg/indapamide 0.625 mg (Per/Ind) vs enalapril in reducing left ventricular hypertrophy (LVH) in hypertensive patients. This multicentre, controlled, randomised, double-blind, parallel group study is carriedout to assess the variation of left ventricular mass index (LVMI) after treatment, using a centralised control of Mmode echocardiography determinations, and a dedicated software for semi-automatic measurement. Following a 4-week placebo run-in period, hypertensive outpatients aged у18 years, with LVH (LVMI Ͼ120 and 100 g/m 2 for men and women, respectively), are randomised to receive once daily, over 52 weeks, either Per/Ind or enalapril. According to blood pressure levels, the dose may be adjusted. In addition to clinical examinations, ECG, blood pressure, heart rate and laboratory assessments echocardiographic determinations are performed for selection, at baseline, after 24 weeks and

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“…Cardiac magnetic resonance imaging was used as the gold standard, as it has been extensively validated against autopsy in the 3-Dimensional (3-D) measurement of LVM. 8,9 Clinical Investigations continued…”

Section: Introductionmentioning

confidence: 99%

Measurement of Left Ventricular Mass by Contrast Ventriculography

Chhatriwalla

Kramer

Peixoto

et al. 2008

Clinical Cardiology

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Background: Elevated left ventricular mass (LVM) has been shown to be an important predictor of adverse cardiac events. Calculation of LVM using contrast ventriculography, as described by Rackley, involves measuring left ventricular wall thickness in a single plane, with assumptions made about ventricular geometry. Hypothesis: We hypothesized that a modification of the Rackley method, involving multiple measurements of left ventricular (LV) wall thickness in 2 orthogonal planes, may add value in the determination of LVM in patients with LV remodeling and dysfunction. Methods: The LVM was determined in 24 patients with LV dysfunction who had undergone both cardiac magnetic resonance imaging (CMRI) and contrast left ventriculography. Right anterior oblique (RAO) and left anterior oblique (LAO) still frames in diastole were used to measure LV length, chamber area, and wall thickness. From these variables, LV volume, myocardial volume, and LVM were calculated. The LVM calculations using an average wall thickness from the LAO and RAO projections were compared with LVM measured by CMRI. Results: Eighty eight percent of patients had hypertension, 100% had coronary artery disease, and mean left ventricular ejection fraction by contrast left ventriculography was 41±14%. Averaging left ventricular wall thickness from RAO and LAO projections using biplane ventriculography for LVM calculation yielded a strong correlation (r = 0.77, p<0.01) with LVM calculated from CMR. Conclusions: In patients with left ventricular dysfunction, biplane left ventricular wall thickness measurements for contrast ventriculography LVM calculations render a strong correlation with LVM calculated by CMRI.

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Magnetic resonance imaging compared to echocardiography to assess left ventricular mass in the hypertensive patient

Cited by 320 publications

References 34 publications

New Gender-Specific Partition Values for ECG Criteria of Left Ventricular Hypertrophy

New Gender-Specific Partition Values for ECG Criteria of Left Ventricular Hypertrophy

Efficacy of very low dose perindopril 2 mg/indapamide 0.625 mg combination on left ventricular hypertrophy in hypertensive patients: the P.I.C.X.E.L. study rationale and design

Measurement of Left Ventricular Mass by Contrast Ventriculography

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