Magnetic resonance imaging: Lumbosacral lipoma

Komiyama, Masaki; Hakuba, Akira; Inoue, Yuichi; Yasui, Toshihiro; Yagura, Hajime; Baba, Mitsuru; Nishimura, Shüro

doi:10.1016/0090-3019(87)90303-x

Cited by 22 publications

(10 citation statements)

References 12 publications

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“…Systematic differences between different regions in the brain were minimized by comparing relaxation times from similar areas in patients and controls. The calculation of the intrinsic tissue parameters TI and T2 from MR images has been described in previous publications in which the emphasis was on tissue characterization (9)(10)(11)(12)(13). T1 and T2 values are not significantly affected by blood pressure, smoking, alcohol, medications, dietary habits, and demographic factors, and are only slightly correlated with age ( 14).…”

Section: Discussionmentioning

confidence: 99%

Quantitative MR in the diagnosis of multiple sclerosis

Haughton

Yetkin

Rao

et al. 1992

Magnetic Resonance in Med

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In patients with multiple sclerosis (MS), the apparently uninvolved cerebral white matter between demyelinated plaques may have biochemical abnormalities. To what degree the changes in the white matter contribute to symptomatology in MS is unknown. In 39 patients with multiple sclerosis, and in 39 age-matched nondiseased volunteers, T1 and T2 were calculated from spin-echo images in four regions of apparently uninvolved white matter. In three of four white matter areas, the average T1 and T2 were significantly longer in the patients than in the controls. The T1 correlated with the disability, measured by the Kurtzke Extended Disability Status Scale, although the correlation was marginally significant. The results suggest that in patients with MS, white matter disease that is not visualized in MR as distinct foci of abnormal signal intensity may contribute to disease burden and disability.

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Section: Discussionmentioning

confidence: 99%

Quantitative MR in the diagnosis of multiple sclerosis

Haughton

Yetkin

Rao

et al. 1992

Magnetic Resonance in Med

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“…Associated anomalies such as syringomyelia is also clearly demonstrated. However the exact relationships of the lipoma and nerve roots are impossible to assess because of the lack of visualization of the nerve roots with this technique [8]. However in our experience, transverse sections define the lateral extension of the lipoma allowing (to a certain extent) us, to forsee the surgical difficulties.…”

Section: Discussionmentioning

confidence: 98%

MRI study of lumbosacral lipoma in children

et al. 1989

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The authors report 16 cases of lumbosacral lipoma in children studied by MRI. The exact position of the cord and its relationship to the lipoma were well demonstrated in all cases but one. There was as high incidence (25%) of syringomyelia in the terminal conus. Arnold Chiari malformation was never associated, which differentiates lumbosacral lipomas from myelomeningoceles. However, the nerve roots and their relationship to the lipoma were rarely visualized. Despite these drawbacks, MRI is the examination of choice if lumbosacral lipoma is suspected in children.

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“…Although differences exist between mean relaxation parameters for tumor and normal tissues -that allow classical MRI sequences to detect tumors -the overlap in parameter range has resulted in the failure of attempts to employ individual parameters (proton density, T 1 or T 2 ) as a quantitative diagnostic marker or to define individual tissues by their native relaxation properties or proton density. [5][6][7][8] This difference does, however, allow tumor detection on MRI by visual inspection of the difference in T 1 , T 2 , T 2 * or proton density from surrounding normal tissue, a difference that may be variably marked or subtle. In Figure 19.1, images are shown from a patient with an aggressive primary brain Figure 19.1 Computerized tomography and MR images of a left temporal lobe glioblastoma multiforme in a 47-year-old man.…”

Section: Clinical Use Of ''Weighted'' Sequencesmentioning

confidence: 99%

CHAPTER 19. Magnetic Resonance Imaging Techniques in Cancer

Morris¹,

O’Connor²,

Jackson³

2013

New Developments in NMR

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MRI has become an integral and essential part of cancer management, providing non-invasive, radiation-free visualization of the presence, extent and spread of tumors within the body. Clinical and pre-clinical oncology researchers have proven to be early adopters of advanced MR technology and many groups focus on the development and validation of novel imaging approaches. The clinical uptake of more advanced MR imaging techniques such as diffusion weighted imaging (DWI) and dynamic contrast enhanced MRI (DCE-MRI) is slower and has occurred only in recent years. This relatively late adoption largely reflects the difficulties in translating complex acquisition or analysis techniques into the clinical setting but also the delay inherent in validating novel imaging techniques for clinical use.Increasingly, there is a requirement for quantitative metrics, which reflect physiological or disease processes (e.g. quantified images of tumor blood flow). These ''imaging biomarkers'' and their identification, validation and clinical translation have become the paradigm for the development of novel techniques in oncological MRI.

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Magnetic resonance imaging: Lumbosacral lipoma

Cited by 22 publications

References 12 publications

Quantitative MR in the diagnosis of multiple sclerosis

Quantitative MR in the diagnosis of multiple sclerosis

MRI study of lumbosacral lipoma in children

CHAPTER 19. Magnetic Resonance Imaging Techniques in Cancer

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