Magnetic resonance imaging of bone marrow in oncology, Part 2

Hwang, Sinchun; Panicek, David M.

doi:10.1007/s00256-007-0308-4

Cited by 85 publications

(88 citation statements)

References 58 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Otake et al found markedly decreased contrast enhancement of bone marrow both inside and outside the radiation portal (Hwang and Panicek 2007 ;Otake et al 2002 ). Interpretation of these fi ndings differs, the most attractive explanation being fatty conversion due to scatter irradiation (Otake et al 2002 ;Blomlie et al 1995 ).…”

Section: Radiation-induced Changes On Normal Bone Marrowmentioning

confidence: 80%

“…The composition B.Jobke and H.Bloem gradually changes from birth to adulthood with the conversion from red to yellow marrow and reaches a static stage between 25 and 30 years of age. The speed of conversion is gender dependent, faster in males than in females (Hwang and Panicek 2007a ;Shapiro 2006 ). Bone marrow fatty conversion progressively starts distally in the extremities and migrates proximally within the extremities towards the axial skeleton in terms of the whole body and from the diaphysis to the metaphysis on the level of the long bones.…”

Section: Bone Marrow Conversion and Reconversionmentioning

confidence: 99%

“…In young children, red marrow is approximately 40 % water, 40 % fat, and 20 % proteins, while by 70 years of age, that proportion has changed to 60 % fat and 10 % proteins. Red marrow consists of 60 % hematopoietic cells and 40 % adipocytes in the young but only about 30 % hematopoietic cells in the elderly (Poe 2010 ;Burdiles and Babyn 2009 ;Hwang and Panicek 2007 ;Steiner et al 1993 ;Snyder et al 1975 ). In contrast, yellow marrow (fatty marrow) is nearly entirely composed of adipocytes (95 %) and its chemical composition is 80 % fat, 15 % water, and 5 % proteins (Hwang and Panicek 2007 ;Steiner et al 1993 ;Snyder et al 1975 ).…”

Section: Bone Marrow Composition and Distributionmentioning

confidence: 99%

See 2 more Smart Citations

Female Pelvis: Genital Organs

Forstner

Cunha²

2015

Imaging of Complications and Toxicity Following Tumor Therapy

View full text Add to dashboard Cite

Medical Radiology-Diagnostic Imaging is a unique series that aims to document the most innovative technologies in all fi elds within diagnostic imaging and interventional radiology, thereby informing the physician in practice of the latest advances in diagnostic imaging and percutaneous imageguided minimally invasive procedures. Th e contents are intended to cover all organs, and all modern imaging techniques and image-guided treatment modalities, with special emphasis on applications in clinical practice. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. Medical Radiology -Radiation Oncology is a unique series that aims to document the most innovative technologies in all fi elds within radiology, thereby informing the physician in practice of the latest advances in diagnostic and treatment techniques. Th e contents range from contemporary statements relating to management for various disease sites to explanations of the newest techniques for tumor identifi cation and of mechanisms for the enhancement of radiation eff ects, with the emphasis on maximizing cure and minimizing complications. Each volume is a comprehensive reference book on a topical theme, and the editors are always experts of high international standing. Contributions are included from both clinicians and researchers, ensuring wide appeal. This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifi cally the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfi lms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specifi c statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. The publisher, the authors and the editors are safe to assume that the advice and information in this book are believed to be true and accurate at the date of publication. Neither the publisher nor the authors or the editors give a warranty, express or implied, with respect to the material contained herein or for any errors or omissions that may have been made. AbstractA precise knowledge of antineoplastic drugs is an indispensable basis for the care of patients with cancer. The mechanisms of action and resistance, cross-resistance patterns, pharmacodynamics and pharmacokinetics, pharmacological interaction, and last but not least potential adverse effects should be part of this knowledge. As contemporary cancer care requires interdisciplinary and multiprofessional structures, the radiologist is an important a...

show abstract

Section: Radiation-induced Changes On Normal Bone Marrowmentioning

confidence: 80%

Section: Bone Marrow Conversion and Reconversionmentioning

confidence: 99%

Section: Bone Marrow Composition and Distributionmentioning

confidence: 99%

See 1 more Smart Citation

Female Pelvis: Genital Organs

Forstner

Cunha²

2015

Imaging of Complications and Toxicity Following Tumor Therapy

View full text Add to dashboard Cite

show abstract

“…Although rare, malignant lesions such as lymphoma can mimic the signs and symptoms of, or arise from infection, and should be considered in differential diagnoses (7). Because she had no underlying malignancy, it was unlikely that the lesion would prove metastatic, but metastasis may also appear as rim-enhancing lesion (9).…”

Section: Index Termsmentioning

confidence: 99%

Necrotic Bone Involvement in an Adult Afflicted with B-Cell Precursor Acute Lymphoblastic Leukemia Mimicking Osteomyelitis: A Case Report

Kim

Kwon

Chong

et al. 2018

J Korean Soc Radiol

View full text Add to dashboard Cite

show abstract

“…It is known that treatment induces edema, return of marrow fat, sclerosis or fibrosis [22], resulting in MR signal changes of the bone marrow which are time-and dose-dependent [23]. While T1w reflects marrow replacement and is rather independent of associated sclerosis, STIR reflects more the lesion composition (water content, fibrosis and sclerosis) and shows variable signal [24,25].…”

mentioning

confidence: 99%

MR Diagnosis of Bone Metastases at 1.5 T and 3 T: Can STIR Imaging Be Omitted?

Ohlmann-Knafo¹,

Tárnoki²,

Tárnoki³

et al. 2015

Fortschr Röntgenstr

View full text Add to dashboard Cite

Musculoskeletal System 924OhlmannObjective: To date, no prospective comparative study of the diagnostic value of STIR versus T1-weighted (T1w) sequences at both 1.5 T and 3 T has been performed with special focus on the detectability of bone metastases. Materials and Methods: 212 oncological patients had a whole-body MRI at 1.5 T and/or at 3 T. The standard protocol comprised STIR and T1w sequences. All patients who showed typical signs of bone metastases were included in the study. Evaluation of the images was performed by the calculation of the number of metastases by three independent readers and by visual assessment on a 4-point scale.Results: 86 patients fulfilled the inclusion criteria. The total number of metastases was significantly higher on T1w than on STIR images at both field strengths (p < 0.05). T1w revealed a sensitivity of 99.72 % (3 T) and 100.00 % (1.5 T) versus STIR with 70.99 % (3 T) and 79.34 % (1.5 T). In 53 % (38/ 72) of all patients, STIR detected fewer bone metastases in comparison with T1w at 3 T. At 1.5 T, STIR showed inferior results in 37.5 % (18/48) of all patients. Qualitative analysis indicated a significantly better lesion conspicuity, lesion delineation and an improved image quality on T1w compared to STIR imaging at both field strengths (p < 0.05) with similar results for T1w at 1.5 T and 3 T, but inferior results for STIR especially at 3 T. Conclusion: The whole-body MRI protocol for the detection of bone metastases could safely be limited to the T1w sequence in adults, especially at 3 T. There is no need for an additional STIR sequence. These initial results will have a major impact on the department's workflow if confirmed by larger studies as they will help reduce examination time and therefore save financial resources.

show abstract

Magnetic resonance imaging of bone marrow in oncology, Part 2

Cited by 85 publications

References 58 publications

Female Pelvis: Genital Organs

Female Pelvis: Genital Organs

Necrotic Bone Involvement in an Adult Afflicted with B-Cell Precursor Acute Lymphoblastic Leukemia Mimicking Osteomyelitis: A Case Report

MR Diagnosis of Bone Metastases at 1.5 T and 3 T: Can STIR Imaging Be Omitted?

Contact Info

Product

Resources

About