Magnetic Resonance Imaging of Central Nervous System Vasculitis A Case Report of Henoch‐Schönlein Purpura

Abstract

Magnetic resonance imaging of central nervous system vasculitis. A case report of Henoch-Schiinlein purpura. Acta Paediatr Scand 79: 710,1990. A case of Henoch-Schliinlein purpura (HSP) with central nervous system vasculitis diagnosed by MRI is discussed.

Cerebral vasculitis in Henoch-Schönlein purpura: a case report with sequential magnetic resonance imaging

“…Hence we diagnosed cerebral vasculitis with HSP. MRI is much more sensitive than other imaging methods for CNS lesions, including vasculitis [7,11], and can identify the lesions as having a high signal intensity ("being bright"). As it is non-invasive atraumatic, and without known specific complications, it appears to be the best diagnostic tool available for the detection of cerebral vasculitis.…”

“…Although the possible contribution of hypertensive or uremic encephalopathy, metabolic abnormalities, corticosteroid therapy, electrolyte abnormalities, or cerebral vasculitis has been suggested, the precise etiology of the neurological manifestations in each patient has not been identified [3,7,9,10].…”

“…Although Henoch-Sch6nlein purpura (HSP) may involve various organs, as a systemic vasculitis [1], there are only a few reports of central nervous system (CNS) complications [2][3][4][5][6][7][8] and the diagnosis of vasculitic involvement of the CNS is difficult. Hypertensive or uremic encephalopathy, metabolic abnormalities, electrolyte abnormalities, or cerebral vasculitis were suggested as the possible causes of the neurological manifestations [3,7,9,10].…”

“…Hypertensive or uremic encephalopathy, metabolic abnormalities, electrolyte abnormalities, or cerebral vasculitis were suggested as the possible causes of the neurological manifestations [3,7,9,10]. Magnetic resonance imaging (MRI) of the brain is the modality of choice for the evaluation of the CNS disease, and yet only one 10-year-old boy who presented with visual loss has been documented and followed with MRI [7]. We report a CNS complication in a 5-year-old girl with HSP evaluated with MRI after several seizures of sudden onset during the course of the disease.…”

Cerebral hemorrhage in Henoch-Schoenlein syndrome

“…Mild symptoms may be caused by intracranial hypertension, cerebral edema and metabolic disorders, all of which often occur in HSS. The neurological symptoms vary with the area involved and the severity of the cerebral vasculitis, which can easily be detected by MRI [6]. Intracranial hemorrhage ( Table 1) is an extremely rare complication of the disease; we have only been able to find five cases reported in the literature [2,4,5,7,11].…”