1996
DOI: 10.2176/nmc.36.72
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Magnetic Resonance Imaging of Cold Injury-induced Brain Edema in Rats

Abstract: The chronological changes of blood-brain barrier disruption, and diffusion and absorption of edema fluid were investigated in rats with cold-induced brain injury (vasogenic edema) using magnetic resonance imaging. Contrast medium was administered intravenously at 3 and 24 hours after lesioning as a tracer of edema fluid. Serial T1-weighted multiple-slice images were obtained for 180 minutes after contrast administration.Disruption of the blood-brain barrier was more prominent at 24 hours after lesioning than a… Show more

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