Magnetic Resonance Imaging of Recurrent Adult Granulosa Cell Tumor of the Ovary: A Retrospective Analysis of 11 Cases

Abstract

Objective The aim of the study was to characterize magnetic resonance imaging findings in patients with recurrent ovarian adult granulosa cell tumors (AGCTs). Methods Clinical and magnetic resonance imaging manifestations of recurrent AGCTs were evaluated in 11 patients. Results Initial recurrences of AGCT were diagnosed between 13 months and 30 years (mean, 11.3 years). Recurrent tumors were located in the pelvic peritoneum, the abdominal peritoneum, the retroperitoneum, and bone. The number of recurrent tumors varied from 1 to 5. Tumors varied in morphology and all margins were well circumscribed. The internal structures noted were as follows: multilocular cystic and solid and cystic. Furthermore, internal hemorrhage and sponge-like multicystic components were identified. Conclusions Ovarian AGCTs recurred in the pelvic peritoneum, abdominal peritoneum, and the retroperitoneal lymph nodes. Large recurrent AGCTs were commonly well circumscribed, round or lobulated, and multilocular cystic or solid and cystic. Moreover, they frequently included internal hemorrhage and sponge-like multicystic components.

Transition of ovarian granulosa cell tumor from a solid mass to a cystic mass in two months on MR imaging in an adult woman: A case report

“… [9] , the 5- and 10-year overall survival (OS) was excellent, offering a 97% and 95% rate respectively, and the 5- and 10-year disease-free survival rate was 91.8% and 71.6%, respectively. However, recurrences have been reported even 30 years after initial surgery, underpinning the importance of long-term follow-up observation [ 10 , 11 ].

Fig.

…”

Endometrioid adenofibroma of ovary: A case report and review of literature

“…Due to the scattered solid and cystic parts of the tumor, it shows a “spongy” appearance on imaging. [23]…”

“…Due to the scattered solid and cystic parts of the tumor, it shows a "spongy" appearance on imaging. [23] Surgery is the main treatment of endometrioid adenofibroma, the treatment effect can be achieved by complete removal of the ovaries and fallopian tubes or the tumor, and rare cases can recur.…”