Magnetic resonance imaging of solid urethral and peri-urethral lesions

Gaizo, Andrew Del; Silva, Alvin C.; Lam-Himlin, Dora; Allen, Brian C.; Leyendecker, John R.; Kawashima, Akira

doi:10.1007/s13244-013-0259-3

Cited by 28 publications

(15 citation statements)

References 26 publications

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“…Elastin-rich submucosa appears comparatively hyperintense (arrowhead), and the innermost mucosa (dotted arrow) appears hypointense. b Coronal, and c sagittal T2-weighted images showing similar appearance of urethra; mucosa is not well appreciated (b bladder, v vagina) Table 1 Summary of an ideal magnetic resonance imaging of the female urethra protocol [16,19,20,40] Technique…”

Section: Urethral Diverticulummentioning

confidence: 99%

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MRI of female urethra and periurethral pathologies

et al. 2015

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Section: Urethral Diverticulummentioning

confidence: 99%

“…These include a range of benign and malignant lesions. Leiomyomas are an example of benign, solid, periurethral lesions that arise from the urethra, bladder neck, or vagina [20]. These usually demonstrate homogeneous low signal intensity on T1W images and variable signal intensity on T2W images (Fig.…”

Section: Solid Periurethral Lesionsmentioning

confidence: 99%

MRI of female urethra and periurethral pathologies

et al. 2015

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“…Although some reports are available in the literature, most of them elaborate either on pathological [2,3] or radiological [7,8] aspects. Therefore, treatment of such patients remains a challenge.…”

Section: Discussionmentioning

confidence: 99%

“…The distinction between urethral, peri-urethral, and anterior vaginal wall lesions may be difficult because of their anatomic proximity and overlapping clinical features. Imaging techniques such as computed tomography/magnetic resonance (CT/MR) (preferably MR) are helpful in diagnosis [7,8]. Cysto-urethrogram helps in excluding the urethral origin and invasion.…”

Section: Purposementioning

confidence: 99%

High-dose-rate interstitial brachytherapy for female peri-urethral cancer

Sharma¹,

Gandhi²,

Bhatla

et al. 2016

jcb

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Purpose: Peri-urethral cancer (PUC) in females is a rare malignancy. Surgery is not usually contemplated due to associated morbidity. Radiation therapy (RT) can be employed in the form of interstitial brachytherapy (IBT) alone for early lesions, and external beam radiation therapy (EBRT) with or without IBT for advanced lesions. We report our first experience in the literature to evaluate the role of high-dose-rate (HDR) IBT in female PUC.Material and methods: Between 2008 and 2013, 10 female patients with PUC (5 primary and 5 recurrent) were treated with HDR-IBT with or without EBRT at our center. Size of the lesion ranged from 1.5 cm to 5.0 cm. A 2-3 plane free-hand implant was performed using plastic catheters. The prescribed dose of HDR-IBT was 42 Gy in 14 fractions for brachytherapy alone (5 patients), and 18-21 Gy for the boost along with EBRT (5 patients). Patients were followed up regularly for assessment of disease control and toxicity.Results: At a median follow up of 25 months, six patients were disease free at their last follow up. Four patients developed recurrence: 2 at inguinal nodes, 1 at local site, and 1 at both local as well as inguinal nodes. Moist desquamation was the commonest acute toxicity observed in all 5 patients treated with IBT alone, which healed within 4 weeks' time. Overall, grade II delayed complication rate was 30%.Conclusions: Though small sample size, the results of our study have shown that HDR-IBT provides good loco-regional control with acceptable toxicity for female PUC.

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“…Lastly, there was a review conducted recently that addressed the utility of MRI in the setting of urethral and periurethral solid soft-tissue lesions [19]. Despite no recent studies on the topic, the historical literature suggested that MRI is most useful for male urethral tumors/solid lesions that are stage II or higher (due to lack of periurethral invasion in stage I disease, which limits MRI detection ability).…”

Section: Magnetic Resonance Urethrographymentioning

confidence: 99%

Three-Dimensional Imaging of Urethral Stricture Disease and Urethral Pathology for Operative Planning

2016

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Diagnosing urethral pathology can prove difficult, as clinically, the presentation is often nonspecific and may be suggestive of multiple etiologies. Therefore, detailed and accurate urethral imaging in both males and females is critical. Since the early 1900s, conventional imaging studies including RUG and VCUG, with adjunct cystourethroscopy, have remained the gold standard diagnostic techniques to evaluate urethral pathology. However, limitations of conventional imaging have generated interest in finding alternative imaging modalities with comparable, if not superior, diagnostic accuracy, the goal being a more complete assessment of urethral pathology and anatomy that would allow for appropriate surgical planning. Imaging modalities with three-dimensional (3D) capabilities may provide more comprehensive information regarding urethral diseases through a more detailed illustration of periurethral soft tissue structures. Whether or not these imaging modalities will replace conventional studies is unclear, though there is an increasing body of literature that support their use.

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Magnetic resonance imaging of solid urethral and peri-urethral lesions

Cited by 28 publications

References 26 publications

MRI of female urethra and periurethral pathologies

MRI of female urethra and periurethral pathologies

High-dose-rate interstitial brachytherapy for female peri-urethral cancer

Three-Dimensional Imaging of Urethral Stricture Disease and Urethral Pathology for Operative Planning

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