Magnetic Resonance Imaging of the Transplanted Kidney

Renal fibrosis threatens kidney viability and fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the kidney, quantifiable as elasticity and viscosity. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. The ability to detect fibrosis early and monitor it regularly with sufficient sensitivity and specificity is an active area of research. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV), that quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency, offers a potential tool to determine renal elasticity and viscosity in vivo. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in the kidney.

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Measurements of swine renal cortex shear elasticity and viscosity with Shearwave Dispersion Ultrasound Vibrometry (SDUV)

Amador

Urban

Warner

2009

2009 IEEE International Ultrasonics Symposium

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Fibrosis has been associated with altered tissue structure affecting the biomechanical properties of the organs, quantifiable as elasticity and viscosity. Renal fibrosis threatens kidney viability. Evaluation of renal fibrosis by conventional imaging modalities is difficult. Importantly, early detection of renal fibrosis may guide therapy and eliminate invasive biopsy procedures. A newly emerging method called Shearwave Dispersion Ultrasound Vibrometry (SDUV) offers a potential tool to determine renal elasticity and viscosity in vivo. SDUV quantifies both elasticity and viscosity by evaluating dispersion of shear wave propagation speed versus its frequency. The purpose of this study was to evaluate the feasibility of SDUV for in vitro measurements of renal cortex elasticity and viscosity in swine kidney.

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Magnetic Resonance Imaging of the Transplanted Kidney

Cited by 3 publications

References 20 publications

Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility

Acoustic radiation force impulse imaging of the abdomen: demonstration of feasibility and utility

In vitro renal cortex elasticity and viscosity measurements with shearwave dispersion ultrasound vibrometry (SDUV) on swine kidney

Measurements of swine renal cortex shear elasticity and viscosity with Shearwave Dispersion Ultrasound Vibrometry (SDUV)

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