Magnetic resonance imaging of the small bowel in children with idiopathic inflammatory bowel disease: evaluation of disease activity

Alexopoulou, Efthymia; Roma, Elefthería; Loggitsi, Dimitra; Economopoulos, Nikolaos; Papakonstantinou, Olympia; Panagiotou, Ioanna; Pahoula, Ioanna; Kelekis, Nikolaos

doi:10.1007/s00247-009-1272-z

Cited by 40 publications

(27 citation statements)

References 28 publications

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“…Nevertheless, the combination of ADC values and perfusion parameters makes it possible to improve specificity. In their study of children with chronic inflammatory bowel disease, Alexopoulou et al showed that the percentage-based enhancement of the intestinal wall was significantly higher in patients with abnormal C-reactive protein (CRP) values, i. e. with acute inflammation parameters, than in patients with normal CRP values [51]. DCE-MRI requires contrast medium administration within a strictly defined timeframe to allow the quantitative and qualitative analysis of time-signal- Fig.…”

Section: Dynamic Contrast Enhanced (Dce) Mrimentioning

confidence: 99%

Magnetic Resonance Imaging of the Bowel: Today and Tomorrow

Kinner

Hahnemann

Forsting

et al. 2015

Fortschr Röntgenstr

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Magnetic resonance imaging of the small bowel has been feasible for more than 15 years. This review is meant to give an overview of typical techniques, sequences and indications. Furthermore, newly evaluated promising techniques are presented, which have an impact on the advance of MR imaging of the small and large bowel. Key Points: ??T2-weighted sequences both with and without fat saturation and T1-weighted fat saturated sequences prior to and following intravenous injection of a gadolinium-based contrast medium contitute the basics for bowel MR imaging. ??Newer MR applications, such as diffusion-weighted imaging or contrast-enhaced dynamic sequences supply addtional information; they should thus be integrated in a regular sequence protocol f?r bowel MRI. ??Additional new modalities like motility imaging and PET/MRI have to be evaluated in future studies. Citation Format: ??Kinner S, Hahnemann ML, Forsting M et?al. Magnetic Resonance Imaging of the Bowel: Today and Tomorrow. Fortschr R?ntgenstr 2015; 187: 160???167

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Section: Dynamic Contrast Enhanced (Dce) Mrimentioning

confidence: 99%

Magnetic Resonance Imaging of the Bowel: Today and Tomorrow

Kinner

Hahnemann

Forsting

et al. 2015

Fortschr Röntgenstr

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“…This was crucial to obtain a valid dataset in an objective manner for further scrutiny. To our knowledge, there are few studies in the literature on MR imaging of the small bowel in the pediatric population (15)(16)(17)(18)(19). Laghi et al (15) correlated clinical disease activity with contrast enhancement and wall thickening on MRI, whereas, the Alexopoulou group (16) only used contrast enhancement.…”

Section: Correlation Between Clinical and Radiological Findingsmentioning

confidence: 99%

Feasibility of an optimized MR enterography protocol in the evaluation of pediatric inflammatory bowel disease

Bosemani¹,

Öztürk²,

Tekes³

et al. 2013

Journal of the Belgian Society of Radiology

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1 cross-sectional imaging forms an important alternative and complimentary tool to endoscopy in aiding the clinician with diagnosis and management of pediatric inflammatory bowel disease (ibd). the purpose of the study was to evaluate the feasibility of an optimized Magnetic Resonance enterography (MRe) protocol in the evaluation of patients with suspected ibd. 31 children (18 boys and 13 girls) were evaluated by a pediatric gastroenterologist prior to MRe and given a grading for clinical severity of disease. imaging was then performed with oral contrast and a tailored protocol using fast t1/t2 weighted pulse sequences. additionally, contrast and glucagon were administered intravenously. imaging findings were then correlated with the clinical data. excellent distension was achieved in the small bowel. the majority of the studies were of diagnostic quality with no motion artifacts. imaging findings showed statistically significant correlation with disease activity. an optimized pediatric MRe protocol is feasible and correlates well with clinical disease activity. this in turn aids the clinician in the management of children with this chronic debilitating disease.

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“…Meanwhile, other studies have demonstrated a correlation between MRE and CDAI (33,46,47) and a correlation between MRE and laboratory markers of inflammation (erythrocyte sedimentation rate/C-reactive protein) (41-43). Only two pediatric studies compared MRE to PCDAI, one demonstrating a statistically significant correlation between disease on MRE and PCDAI (48) and the other demonstrating no correlation between MRE and PCDAI (49).…”

Section: Comparison Of Mre To Disease Activity Indexmentioning

confidence: 99%

Magnetic resonance enterography in crohn’s disease: techniques, interpretation, and utilization for clinical management

Martín

Kalb

Sauer

et al. 2011

Diagn Interv Radiol

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Magnetic resonance imaging of the small bowel in children with idiopathic inflammatory bowel disease: evaluation of disease activity

Abstract: This MR imaging protocol is a safe and well-tolerated method for evaluating disease activity and extraintestinal manifestations of IBD in children.

Cited by 40 publications

References 28 publications

Magnetic Resonance Imaging of the Bowel: Today and Tomorrow

Magnetic Resonance Imaging of the Bowel: Today and Tomorrow

Feasibility of an optimized MR enterography protocol in the evaluation of pediatric inflammatory bowel disease

Magnetic resonance enterography in crohn’s disease: techniques, interpretation, and utilization for clinical management

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