Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion

Trampus, Péter; Goepfert, Christine; Welle, Monika Maria; Henke, Diana; Forterre, Franck; Schweizer, Daniela

doi:10.3389/fvets.2018.00016

Cited by 12 publications

(30 citation statements)

References 17 publications

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“…Our study reports the prevalence and signal characteristics of muscle changes on MRI in dogs with surgically confirmed IVDE. A recently published study (Trampus et al 2018) reported that paravertebral muscle changes occur in 36% of dogs with IVDE, which contrasts with the number we report (6.9%). Possible reasons for this discrepancy are the larger size of our study population and the lack of STIR images in some cases in the other study.…”

Section: Discussioncontrasting

confidence: 99%

“…Non-ambulatory paraparesis was the most common presentation in the MSIC group, whereas the comparator group predominantly remained ambulatory. This difference is in agreement with a previous report (Trampus et al 2018).…”

Section: Discussionsupporting

confidence: 94%

“…The severity of spinal cord compression was assessed for all patients. In accordance to previous studies (Sukhiani et al 1996, Besalti et al 2005, Trampus et al 2018, the severity of compression was not associated with severity of neurological deficits or spinal pain, and also not associated with paravertebral muscle signal changes. Conversely, all dogs with reported spinal pain had more severe spinal compression.…”

Section: Discussionsupporting

confidence: 92%

“…The most commonly extruded IVD spaces, in the MSIC group, were T13 to L1 and T12 to T13, which is consistent with previous studies (McKee 2000, Ferreira et al 2002, Penning et al 2006, Trampus et al 2018. Two cases showed cervical paravertebral signal intensity changes, documenting that these changes can be found beyond the thoracolumbar region.…”

Section: Discussionsupporting

confidence: 90%

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Low‐field magnetic resonance changes in the paravertebral musculature of dogs with acute intervertebral disc extrusion

Furtado¹,

Cherubini²,

Taeymans³

2019

J of Small Animal Practice

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Objectives To describe the MRI features and prevalence of paravertebral muscle signal intensity changes in dogs with acute intervertebral disc extrusion and to search for associations between the signal changes and clinical history, signalment, neurological examination, serum creatine kinase activity and MRI characteristics of the disc herniation. Materials and Methods Medical records and MRI examinations from 688 dogs with surgically confirmed acute intervertebral disc extrusion were reviewed retrospectively. T2‐weighted and STIR MRI sequences were available for 276 cases and were examined for paravertebral muscle signal intensity changes. When present, extension, lateralisation and signal characteristics of these changes were recorded. Exclusion criteria were muscle injections 24 hours before MRI scan, trauma and previous spinal surgery. Results Nineteen dogs met the inclusion criteria. There were signal changes in the multifidus muscle, mostly in the thoracolumbar region and often extending caudally from the level of the intervertebral disc herniation. Two cases had paravertebral muscle signal intensity changes in the cervical region. MRI signal changes were seen more frequently in the muscles of non‐ambulatory dogs. Clinical history and neuro‐examination did not allow differentiation between dogs with and without paravertebral muscle signal intensity changes. Clinical Significance Paravertebral muscle signal intensity changes were observed infrequently in the epaxial musculature of 6.9% dogs with acute intervertebral disc extrusion in both the thoracolumbar and cervical regions. The pathophysiological processes responsible for these MRI changes remain unknown.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 90%

See 2 more Smart Citations

Low‐field magnetic resonance changes in the paravertebral musculature of dogs with acute intervertebral disc extrusion

Furtado¹,

Cherubini²,

Taeymans³

2019

J of Small Animal Practice

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“…In the latter group of dogs, the muscle groups that were affected were in close proximity to the nerve root and meningeal changes, leading to speculation that meningeal disease might extend into adjacent nerve roots and muscles . Alternatively, the observed changes could be secondary to denervation . Denervation can cause diffuse edema throughout an affected muscle, because of shifting of water from intracellular to extracellular spaces .…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics, breed differences, and quality of life in North American dogs with acute steroid‐responsive meningitis‐arteritis

Lau

Nettifee

Early

et al. 2019

Veterinary Internal Medicne

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Background Steroid‐responsive meningitis‐arteritis (SRMA) is a common inflammatory neurologic disorder of dogs for which certain breeds are predisposed. Objectives To determine whether breed differences exist in clinical features, treatment response, and relapse in a population of North American dogs with SRMA, and to evaluate the effect of disease on dogs' quality of life (QoL). Animals Sixty‐one client‐owned dogs with SRMA: 29 dogs identified through an American Kennel Club‐Canine Health Foundation survey and 32 dogs from North Carolina (NC) State Veterinary Hospital. Methods Retrospective case series. Caregivers completed an online survey to assess QoL. Results Breeds represented most often included the Golden Retriever (n = 12), Bernese Mountain Dog (10), Wirehaired Pointing Griffon (9), Boxer (9), and Beagle (6). No breed differences were identified with respect to clinical severity, diagnostic findings, or outcome. Twenty‐nine dogs (48%) had ≥1 disease relapse. There was a significant effect of cerebrospinal fluid nucleated cell count on the frequency of disease relapse ( P = .003), but no relationship was identified between treatment protocol and relapse. Dogs' QoL was associated with the severity of corticosteroid‐related adverse effects ( P = .03), which were dose‐related ( r = .24, P = .02) and more prevalent in Wirehaired Pointing Griffons than in other breeds ( P = .04). Conclusion and Clinical Importance Golden Retrievers and Wirehaired Pointing Griffons should be considered among the breeds recognized to develop SRMA. Treatment with higher corticosteroid dosages is correlated with more severe adverse effects and worse QoL, but it may not improve clinical outcome.

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Low‐field magnetic resonance imaging characteristics of multifocal vertebral lesions in dogs

Furtado¹,

Moris²,

Esmieu³

et al. 2021

Veterinary Record

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Background: There is a lack of information regarding magnetic resonance imaging (MRI) features of polyostotic vertebral lesions in dogs. The aim of this retrospective study was to identify and differenciate low‐field MRI features of aggressive versus benign multifocal vertebral diseases in dogs. Methods: MRI examinations from 49 dogs with polyostotic vertebral lesions were reviewed. Images were evaluated for vertebral intensity changes, expansile lesions, new bone formation, cortical bone interruption, paravertebral musculature changes, lymphadenomegaly, spinal cord compression and spinal cord signal changes. Results: Twenty‐nine dogs with non‐aggressive bone lesions and 20 dogs with aggressive vertebral lesions were included. Non‐aggressive lesions had variable T2‐weighted fast spin‐echo (T2W) signal intensity and the majority displayed low signal intensity on short tau inversion recovery (STIR). Aggressive lesions predominantly had high T2W and STIR signal intensity, with variable signal intensity on T1‐weighted spin‐echo and contrast enhancement. Aggressive lesions were associated with spinal pain (p < 0.01), new bone formation (p = 0.02), spinal cord compression (p < 0.01) and lymphadenomegaly (p < 0.01). Cortical interruption (p < 0.01) and paravertebral musculature changes (p < 0.01) were the strongest indicative imaging features for aggressive lesions. Conclusion: Spinal pain, spinal cord compression, new bone formation, lymphadenomegaly and especially cortical interruption and paravertebral musculature signal intensity changes were the best discriminators for differentiating malignant from benign vertebral lesions.

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Magnetic Resonance Imaging Signal Alterations in Paraspinal Muscles in Dogs with Acute Thoracolumbar Intervertebral Disk Extrusion

Cited by 12 publications

References 17 publications

Low‐field magnetic resonance changes in the paravertebral musculature of dogs with acute intervertebral disc extrusion

Low‐field magnetic resonance changes in the paravertebral musculature of dogs with acute intervertebral disc extrusion

Clinical characteristics, breed differences, and quality of life in North American dogs with acute steroid‐responsive meningitis‐arteritis

Low‐field magnetic resonance imaging characteristics of multifocal vertebral lesions in dogs

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