Magnetic Resonance Spectroscopy of Pediatric Brain Tumors

Gill, Sharon A.; Panigrahy, Ashok; Arvanitis, Theodoros N.; Peet, Andrew C.

doi:10.1007/978-1-4419-5864-8_5

Cited by 2 publications

(1 citation statement)

References 63 publications

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“…[2] Despite the fact that the actual incidence and prevalence worldwide is still remains in accurately measured or detected, with 80% of patients with malignant brain tumors die from the disease.…”

Section: Introductionmentioning

confidence: 99%

Correlation of Magnetic Resonance Spectroscopy with Histopathology of Brain Biopsies

2017

IJSR

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Abstract:The pathology of human tissue can be determined by magnetic resonance spectroscopy (MRS) but it was a controversial field for over 20 years. Now MRS on human biopsies identifies disease processes, neoplastic status, and prognostic variables with high accuracy. The MRS databases were compared with careful and specialized histology,. The MR method is fast, accurate, and robust and for most organs complements routine histopathological diagnosis. Study was performed to evaluate the rule of Magnetic Resonance Spectroscopy in diagnosis of brain tumors compare by histopathology. A total of 38 patients were examined in this study. The data collected from three hospitals in Khartoum state from 2014 to July 2015. The patients were examined with the own department protocol using Magnetic resonance machine. The study founded that (86.8%) of patients examined by Spectroscopy have same results compare to the histopathology results. Conclusion: MRS is an accurate, noninvasive diagnostic technique for quantifying brain tumors.

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Section: Introductionmentioning

confidence: 99%

Correlation of Magnetic Resonance Spectroscopy with Histopathology of Brain Biopsies

2017

IJSR

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Proton MRS imaging in pediatric brain tumors

Zarifi

Tzika

2016

Pediatr Radiol

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Magnetic resonance (MR) techniques offer a noninvasive, non-irradiating yet sensitive approach to diagnosing and monitoring pediatric brain tumors. Proton MR spectroscopy (MRS), as an adjunct to MRI, is being more widely applied to monitor the metabolic aspects of brain cancer. In vivo MRS biomarkers represent a promising advance and may influence treatment choice at both initial diagnosis and follow-up, given the inherent difficulties of sequential biopsies to monitor therapeutic response. When combined with anatomical or other types of imaging, MRS provides unique information regarding biochemistry in inoperable brain tumors and can complement neuropathological data, guide biopsies and enhance insight into therapeutic options. The combination of noninvasively acquired prognostic information and the high-resolution anatomical imaging provided by conventional MRI is expected to surpass molecular analysis and DNA microarray gene profiling, both of which, although promising, depend on invasive biopsy. This review focuses on recent data in the field of MRS in children with brain tumors.

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Magnetic Resonance Spectroscopy of Pediatric Brain Tumors

Cited by 2 publications

References 63 publications

Correlation of Magnetic Resonance Spectroscopy with Histopathology of Brain Biopsies

Correlation of Magnetic Resonance Spectroscopy with Histopathology of Brain Biopsies

Proton MRS imaging in pediatric brain tumors

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