Magnetic Stimulation in the Treatment of Partial Seizures

Abstract

We have recently demonstrated that Magnetoencephalographic (MEG) brain measurements in patients with seizure disorders show significant MEG activity often in the absence of conventional EEG abnormalities. We localized foci of seizure activity using the mapping technique characterized by the ISO-Spectral Amplitude (ISO-SA) on the scalp distribution of specified spectral components or frequency bands of the emitted MEG Fourier power spectrum. In addition, using an electronic device, we utilized the above recorded activity to emit back the same intensity and frequency of magnetic field to the presumed epileptic foci. Using this method we were able, over the past two years, successfully to attenuate seizure activity in a cohort of over 100 patients with various forms of epilepsy. We now present in more detail three randomly selected patients with partial seizures in whom application of an external artificial magnetic field of low intensity produced a substantial attenuation of seizure frequency during an observation period extending from 10 to 14 months. All patients had previously obtained only partial response to conventional anticonvulsant therapy. Attenuation in seizure frequency was associated with normalization of the MEG activity. These cases demonstrate that artificial magnetic treatment may be a valuable adjunctive procedure in the management of partial seizures. The possible mechanisms underlying the anticonvulsant properties of magnetic stimulation at both cellular and systemic levels are discussed. Specifically, since the pineal gland has been shown to be a magnetosensitive organ which forms part of a combined compass-solar clock system, and since it exerts an inhibitory action on seizure activity in both experimental animals and humans, we discuss the potential pivotal role of the pineal gland in the long term anticonvulsant effects of external artificial magnetic stimulation.

Quantitative Evidence for Direct Effects between Earth-Ionosphere Schumann Resonances and Human Cerebral Cortical Activity

“…The other classical "frequency" bands associated with the human EEG are delta (1-4 Hz), which are the highest amplitude time-variations associated with Stage IV sleep, beta (13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) and gamma (30 to 50 Hz) patterns. The ranges are effectively arbitrary and related to EEG features associated with particular behaviors or power densities.…”

“…Although these intensities appear small, experimental application of pT-intensity, spatial and temporally-patterned magnetic fields have been reported to produce discernable improvement in some clinical disorders, such as Tourette's and multiple sclerosis [21] as well as some electrical foci associated with partial complex seizures [22].…”

Enhanced Power within a Predicted Narrow Band of Theta Activity During Stimulation of Another by Circumcerebral Weak Magnetic Fields After Weekly Spatial Proximity: Evidence for Macroscopic Quantum Entanglement?

“…This means that for the threshold value of energy of 4.6 x 10 -33 J to be achieved, the applied field must be about 2 x 10 -10 T which is within the range Anninos et al (1991) have suggested is the operating intensity of the brain. Such energies would be expected to affect the rotational symmetry of the electron in either its spin or rotation.…”

Effect of Weak Magnetic Fields on Biological Systems

“…Recently, Professor Reuven Sandyk reported on the efficacy of 2 x gauss fields in the treatment of epilepsy and Parkinson's disease (cf. Anninos et al, 1991;Sandyk et al, in press; in press a; Sandyk, in press b). Frequencies of 2-7 Hz have been utilized.…”