We report a colossal resistance drop around insulator-metal transition temperature (TMI) in Sm0.5SSr0.4SMn03 induced by direct current. Polycrystalline samples of Sm0.5SSr0.4SMn03 were synthesized through solid state reaction method, They have been investigated by X-ray diffraction for phase evaluation, scanning electron microscopy for grain morphology and de resistivity measurement techniques for resistivity-temperature behavior. The resistivity-temperature behavior has been measured with different biasing currents (1 rnA, 2.5 rnA,S rnA, lOrnA and 50 rnA), With increasing biasing current, the resistivity of the samples decreased drastically, The change in the resistivity of the samples for bias currents 1 rnA and 50 rnA at TMI was found to be~2560%, This phenomenon of electroresistance is discussed in view of strong interaction between carrier spins and localized spins in Mn ions and percolative mechanism of phase-separation.