Magnetically activated microcapsules as controlled release carriers for a liquid PDMS cross-linker

Abstract

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Liquid–Liquid Encapsulation of Ferrofluid Using Magnetic Field

“…The ferrofluids, which are colloidal suspensions of iron oxide MNPs (size 10 nm) in oil or water dispersion medium, are exceedingly used for magnetic drug targeting, [17][18][19] and antibody extraction. [20] Encapsulated magnetic microdroplets can be fabricated using techniques involving polymerization-based chemical methods, [13,21,22] emulsification, [22] phase separation, [23][24][25] layerby-layer templating, [26][27][28] and droplet microfluidics. [29][30][31][32][33][34][35][36][37] In the case of the polymerization-based method, an emulsion consisting of the magnetic liquid and an immiscible dispersed phase (such as water) is synthesized.…”

“…Encapsulated magnetic microdroplets can be fabricated using techniques involving polymerization‐based chemical methods, [ 13,21,22 ] emulsification, [ 22 ] phase separation, [ 23–25 ] layer‐by‐layer templating, [ 26–28 ] and droplet microfluidics. [ 29–37 ] In the case of the polymerization‐based method, an emulsion consisting of the magnetic liquid and an immiscible dispersed phase (such as water) is synthesized.…”

Manipulation of Ferrofluid‐Wrapped Drops: Translation, Coalescence, and Release

“…Similarly, ferrofluids, which are colloidal suspensions of magnetic nanoparticles in a base fluid, have emerged as a popular choice in magnetic manipulation systems. [12,50] Ferrofluid manipulation finds application in liquid cargo transportation, [51][52][53] micro-lens fabrication, [19,20] droplet sorting, [13,34,54] controlled chemical synthesis, [13] oil recovery, [55] among others. Importantly, it has been shown that manipulation of encapsulated magnetic cargo can be used for targeted drug delivery for therapeutic applications.…”

“…It should also facilitate a wider range of core and shell volume as required. Motivated by these gaps, the research community has investigated various encapsulation techniques for magnetic fluids, including phaseseparation, [55,59] microfluidics, [8,34,54,60] and emulsification. [61] Recently, Banerjee et al [62] from our group demonstrated a facile magnet-assisted framework that facilitates the encapsulation of multiple ferrofluid droplets inside a thin polydimethylsiloxane (PDMS) shell.…”

“…It should also facilitate a wider range of core and shell volume as required. Motivated by these gaps, the research community has investigated various encapsulation techniques for magnetic fluids, including phase‐separation, [ 55,59 ] microfluidics, [ 8,34,54,60 ] and emulsification. [ 61 ]…”