Magnetically controllable generation of ferrofluid droplets

Yan, Qifan; Xuan, Shouhu; Ruan, Xinzhong; Wu, Jie; Gong, Xinglong

doi:10.1007/s10404-015-1652-7

Cited by 39 publications

(24 citation statements)

References 37 publications

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“…These forces include inertial force, viscous force, interfacial tension, and buoyancy. In some cases, external forces such as electric, 24,25 magnetic, 26,27 and centrifugal forces 28 are also utilized. The balance of these forces determines the fluid behaviour and thus the mechanism of droplet formation.…”

Section: Droplet Generationmentioning

confidence: 99%

Microfluidic fabrication of microparticles for biomedical applications

et al. 2018

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Droplet microfluidics offers exquisite control over the flows of multiple fluids in microscale, enabling fabrication of advanced microparticles with precisely tunable structures and compositions in a high throughput manner. The combination of these remarkable features with proper materials and fabrication methods has enabled high efficiency, direct encapsulation of actives in microparticles whose features and functionalities can be well controlled. These microparticles have great potential in a wide range of bio-related applications including drug delivery, cell-laden matrices, biosensors and even as artificial cells. In this review, we briefly summarize the materials, fabrication methods, and microparticle structures produced with droplet microfluidics. We also provide a comprehensive overview of their recent uses in biomedical applications. Finally, we discuss the existing challenges and perspectives to promote the future development of these engineered microparticles.

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Section: Droplet Generationmentioning

confidence: 99%

Microfluidic fabrication of microparticles for biomedical applications

et al. 2018

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“…in microfluidics, where flow-focusing geometries can be used to separate droplets and control their size, with or without the help of an external controllable magnetic field, (e.g. Tan et al 2010;Yan et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Shape and fission instabilities of ferrofluids in non-uniform magnetic fields

Vieu

Walter

2018

J. Fluid Mech.

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We study static distributions of ferrofluid submitted to non-uniform magnetic fields. We show how the normal-field instability is modified in the presence of a weak magnetic field gradient. Then we consider a ferrofluid droplet and show how the gradient affects its shape. A rich phase transitions phenomenology is found. We also investigate the creation of droplets by successive splits when a magnet is vertically approached from below and derive theoretical expressions which are solved numerically to obtain the number of droplets and their aspect ratio as function of the field configuration. A quantitative comparison is performed with previous experimental results, as well as with our own experiments, and yields good agreement with the theoretical modeling.

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“…For example, electric-field-based droplet manipulation 30 requires materials that can withstand high voltages, and the electrical tapes (Super 88 Vinyl Electrical Tape, 3 M) with 10 kV breakdown voltages are suitable for these applications. In magnetic-field-based droplet manipulation 31 , magnetic tapes (Flexible Magnet Tape, 3 M) can be used to support magnetic fields in the fluid channels. Furthermore, all the above mentioned special tapes are commercially available, which is beneficial to decrease the cost and to increase the accessibility of the acrylic-tape microfluidic devices.…”

Section: Resultsmentioning

confidence: 99%

Reconfigurable Acrylic-tape Hybrid Microfluidics

Ren

Ray

Liu

2019

Sci Rep

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There is a great interest in low-cost, versatile microfluidic platforms of which the fabrication processes are rapid, straightforward, and translatable to industrial mass productions. In addition, it is beneficial for microfluidic devices to be reconfigurable in the field, so that multiple functions can be realized by a minimum number of devices. Here, we present a versatile acrylic-tape platform which allows highly accessible rapid prototyping of microfluidic devices, as well as device reconfiguration to realize different functions. The clean-room-free fabrication and sealing process only requires a laser cutter, acrylic, and tapes and can be done by an untrained person in the field. We experimentally characterized the relationship between the capillary flow speed and the channel height, the latter of which can be well controlled by the fabrication process. Reconfiguration of microfluidic functions was demonstrated on a single acrylic-tape device, thanks to the reversible sealing enabled by functional tapes. Different pumping mechanisms, including on-chip pumps for better portability and syringe pumps for precise fluid control, have been employed for the demonstration of two-phase flow and droplet generation, respectively. The low-cost and versatile acrylic-tape microfluidic devices are promising tools for applications in a wide range of fields, especially for point-of-care biomedical and clinical applications.

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Magnetically controllable generation of ferrofluid droplets

Cited by 39 publications

References 37 publications

Microfluidic fabrication of microparticles for biomedical applications

Microfluidic fabrication of microparticles for biomedical applications

Shape and fission instabilities of ferrofluids in non-uniform magnetic fields

Reconfigurable Acrylic-tape Hybrid Microfluidics

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