“…However, the accuracy of this approach is limited by the measurement of the temperature of the bulk support environment, without considering the difference in temperature between the NCs and their local support environment. With only ILP values, it is difficult or nearly impossible to use these species in scenarios such as catalysis of thermally sensitive compounds or targeted cell death, where a thermal difference is a key aspect of the work. ,,,,,− Here, we have shown that the correlated Debye model can be used directly to calculate the temperature of the NCs, while the values of ILP can be used to extract the local support environment temperature. ,,, Experimentally, the ILP of the local support environment was directly observed with a thermal imaging camera, and the thermal difference between the local support environment and the NCs was directly compared for complete thermal understanding of the system. Therefore, this study is not only the first to use in situ EXAFS-based nanothermometry to extract thermal measurements in inductively heated systems but also the first to jointly use temperature-dependent EXAFS and the unapproximated correlated Debye model for the determination of temperature.…”