Magnetite (Fe3 O4 ) nanoparticles: Are they really safe?

Ramírez, Lenin Pablo

doi:10.17163/lgr.n21.2015.07

Cited by 7 publications

(8 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Such a system has the potential to minimize the side effects and the required dosage of the drugs. However, once the surface-derivatized NPs are inside the cells, the coating is likely digested, leaving the bare particles exposed to other cellular components and organelles, thereby potentially influencing the overall integrity of the cells [152]. Recently, efforts have been made to improve the distribution of anticancer drugs in the human body and decrease their toxic effect [153,154].…”

Section: Targeted Drug Deliverymentioning

confidence: 99%

A biotechnological perspective on the application of iron oxide nanoparticles

et al. 2016

View full text Add to dashboard Cite

In recent decades, magnetic iron nanoparticles (NPs) have attracted much attention due to properties such as superparamagnetism, high surface area, large surface-to-volume ratio, and easy separation under external magnetic fields. Therefore, magnetic iron oxides have potential for use in numerous applications, including magnetic resonance imaging contrast enhancement, tissue repair, immunoassay, detoxification of biological fluids, drug delivery, hyperthermia, and cell separation. This review provides an updated and integrated focus on the fabrication and characterization of suitable magnetic iron NPs for biotechnological applications. The possible perspective and some challenges in the further development of these NPs are also discussed.

show abstract

Section: Targeted Drug Deliverymentioning

confidence: 99%

A biotechnological perspective on the application of iron oxide nanoparticles

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Magnetic nanoparticles (MNP) had super paramagnetism, which was used to generate magnetothermal effect. Under the action of external magnetic field, it can be magnetized quickly, and there was no residual magnetism after removing the external magnetic field (Ramírez, ). There is also a change in paramagnetic state after being heated, which accelerates the conduction of heat caused by the vigorous movement of polar molecules in the thawed fish fillets.…”

Section: Introductionmentioning

confidence: 99%

Effects of different thawing methods on physicochemical properties and structure of largemouth bass (Micropterus salmoides)

Cai

Wan

et al. 2020

Journal of Food Science

View full text Add to dashboard Cite

To evaluate the physicochemical properties and structure of thawed fillets, following six treatments were used: conventional thawing, microwave thawing, microwave or ultrasound combined with vacuum thawing, magnetic nanoparticles combined with microwave or far‐infrared thawing. The thawing loss, cooking loss, pH, color, texture change, water‐holding capacity, and water migration of fish fillets were determined. The total volatile base nitrogen and thiobarbituric acid were used to determine the degree of protein degradation and lipid oxidation. Microscope observations and scanning electron microscope (SEM) were used to observe fiber microstructure. Results indicated that both microwave combined with vacuum thawing and far‐infrared combined with magnetic nanoparticles thawing had desirable physicochemical properties as compared to other thawing methods. The lower total volatile base nitrogen and thiobarbituric acid values had less effect on protein degradation and lipid oxidation of thawing process. Besides, both microwaves combined with vacuum thawing and far‐infrared combined with magnetic nanoparticles thawing samples had no significant difference in immobilized and bond water compared with fresh sample. SEM and microscopic observation showed that the myofibril bundles were arranged regularly and smoothly in microwave combined with vacuum thawing and far‐infrared combined with magnetic nanoparticles thawing samples compared with other thawed methods. Thus, the microwave combined with vacuum thawing and far‐infrared combined with magnetic nanoparticles thawing as potential thawing methods could be used to maintain the quality of thawed fish fillets. Practical Application Largemouth bass (Micropterus salmoides) is a good source of animal protein. The fish needs to be frozen for circulation because of geographical and seasonal factors, so thawing methods can directly affect the quality of thawed fish. The results showed that the microwave combined with vacuum and the magnetic nanoparticles combined with far‐infrared thawing could better maintain the quality of thawed fish.

show abstract

“…Toxicity research usually studies the adverse effects of substances in terms of physical, chemical and biological agents in tested animals and the environment (Abbas et al, 2018; Iqbal et al, 2019). Due to the low toxic effect of magnetite, Fe 3 O 4 nanoparticles, compared to other iron oxides, it is highly recommended for biomedical and biotechnological applications (Iqbal, 2016; Ramírez‐Cando, 2015). It signified with varies multitask applications such as drug delivery, cancer tumour detection, gene therapy, biomolecular separation, in vivo biomolecular detection, tissue repair and Magnetic Resonance Imaging (MRI) (Deng et al, 2014; Ramírez‐Cando, 2015; Wu et al, 2013).…”

Section: Introductionmentioning

confidence: 99%

“…Due to the low toxic effect of magnetite, Fe 3 O 4 nanoparticles, compared to other iron oxides, it is highly recommended for biomedical and biotechnological applications (Iqbal, 2016; Ramírez‐Cando, 2015). It signified with varies multitask applications such as drug delivery, cancer tumour detection, gene therapy, biomolecular separation, in vivo biomolecular detection, tissue repair and Magnetic Resonance Imaging (MRI) (Deng et al, 2014; Ramírez‐Cando, 2015; Wu et al, 2013). For healthcare applications, magnetite nanoparticles remain the only magnetic nanoparticles that have been accepted for clinical applications that also commercially available and approved by Food and Drugs Administration (FDA) (Busquets et al, 2014; Ramírez‐Cando, 2015).…”

Section: Introductionmentioning

confidence: 99%

“…It signified with varies multitask applications such as drug delivery, cancer tumour detection, gene therapy, biomolecular separation, in vivo biomolecular detection, tissue repair and Magnetic Resonance Imaging (MRI) (Deng et al, 2014; Ramírez‐Cando, 2015; Wu et al, 2013). For healthcare applications, magnetite nanoparticles remain the only magnetic nanoparticles that have been accepted for clinical applications that also commercially available and approved by Food and Drugs Administration (FDA) (Busquets et al, 2014; Ramírez‐Cando, 2015). Hence, the surface engineers is recognized such nanoparticles, magnetite, as a modern technology with low toxicity to introduce it to wastewater treatment applications as an environmental benign particles (Thabet et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Synthesis, characterization and potential application of magnetized nanoparticles for photocatalysis of Levafix CA reactive azo‐dye in aqueous effluent

Thabet

Fouad

Ali

et al. 2021

Water & Environment J

View full text Add to dashboard Cite

Dyes represent major environmental concerns since their presence in aqueous effluents posed a threat to the ecological system. This work is focused on developing a sustainable photo-Fenton strategy for efficient Levafix Blue oxidation. Nanostructured magnetite as the precursor of the oxidation technique has been synthesized via a simple co-precipitation technique. Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) were applied to characterize the samples.The experimental dye removal data revealed that almost complete dye removal (99.9%) was attained at pH 3.0 using 800 and 40 mg/L of H 2 O 2 and magnetite reagents, respectively within 30-min of irradiation time. The process follows the first-order reaction model with endothermic and non-spontaneous oxidation reaction in nature with a low activation energy barrier of 14.29 kJ/mol. Finally, the experimental data reveals that magnetite could be easily recovered and recycled up to six treatment cycles with a removal efficiency of 71% confirms the process sustainability.

show abstract

Magnetite (Fe3 O4 ) nanoparticles: Are they really safe?

Cited by 7 publications

References 27 publications

A biotechnological perspective on the application of iron oxide nanoparticles

A biotechnological perspective on the application of iron oxide nanoparticles

Effects of different thawing methods on physicochemical properties and structure of largemouth bass (Micropterus salmoides)

Synthesis, characterization and potential application of magnetized nanoparticles for photocatalysis of Levafix CA reactive azo‐dye in aqueous effluent

Contact Info

Product

Resources

About