Magnetite Nanoparticles: Synthesis and Applications in Optics and Nanophotonics

Dudchenko, N.O.; Pawar, Shweta; Perelshtein, Ilana; Fixler, Dror

doi:10.3390/ma15072601

Cited by 53 publications

(23 citation statements)

References 130 publications

(143 reference statements)

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“…Advances in molecular imaging based on nanoparticles (NPs) have greatly improved the sensitivity and specificity of imaging detection methods [ 27 ]. Further research using NPs loaded with gadolinium (Gd) contrast agents functionalized with ligands specifically targeting overexpressed cancer cell receptors has also achieved encouraging results in animals [ 28 , 29 ].…”

Section: Prospect For Nanoparticle-remodeled Neutrophilsmentioning

confidence: 99%

Approaches for neutrophil imaging: an important step in personalized medicine

et al. 2022

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Neutrophils are the most abundant circulating leukocytes and the first line of defense against invading pathogens. They are key components of the innate immune system. Neutrophils also cause tissue damage in various autoimmune and inflammatory diseases and play an important role in cancer progression. Due to the complex relationship between various diseases and neutrophils, these cells have become potentially important targets for therapeutic interventions. Monitoring neutrophils in the tumor microenvironment is critical for tumor treatment and prognostic analysis but remains challenging. Molecular imaging technology has made great progress as a valuable tool for noninvasively visualizing biological events and establishing effective cancer diagnoses and treatment methods. Molecular probes designed based on the characteristics of neutrophils, such as their flexible morphology, the abundance of surface receptors, and the absence of immunogenicity, have shown great potential. This has created an opportunity for novel ideas and research methods for the diagnosis and targeted therapy of inflammatory diseases and tumors, with the goal of integrated diagnosis and treatment. This review discusses the diverse tumor detection and diagnostic imaging strategies based on neutrophils. It is anticipated that neutrophil-based imaging will soon be gradually integrated into clinical applications.

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Section: Prospect For Nanoparticle-remodeled Neutrophilsmentioning

confidence: 99%

Approaches for neutrophil imaging: an important step in personalized medicine

et al. 2022

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“…Fe 3 O 4 nanoparticles are one of the most prepared and studied ferrite systems since they can be used in multiple different areas such as engineering applications, environmental technologies, and biomedicine. − Magnetite is one of the most attractive materials in the industrial field; apart from illustrating superparamagnetic behavior, it is nontoxic and easy to prepare with low-cost synthesis conditions. Also, it presents a microstructure dependent on different synthesis conditions such as temperature or doping, which makes the magnetite system a more versatile and application-rich material.…”

Section: Introductionmentioning

confidence: 99%

Insights into the Magnetic Properties of Single-Core and Multicore Magnetite and Manganese-Doped Magnetite Nanoparticles

et al. 2023

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Assembled magnetite nanoparticles with oriented attachment have been prepared to study the effect of autoassembling on their heating efficiency. Their magnetic properties have been compared with those corresponding to singlecore particles, also prepared in this study. It has been found that not only particle size and shape are determinant factors on the magnetic behavior but also the interparticle interactions as well since they drastically modify the effective magnetic volume related to the magnitude of the superparamagnetic moment. The high values of the superparamagnetic moment observed for all of the samples in a broad temperature range are probably a consequence of the dipolar interactions. Moreover, the sample exhibiting both large anisotropy barriers and superparamagnetic moment at 300 K is the one presenting the largest SAR values. Therefore, the superparamagnetic behavior at room temperature together with the magnetic hardness seem to be key factors for the heat generation.

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“…Co-precipitation is an important procedure and the most widely used for the synthesis of Fe 3 O 4 nanoparticles. It is spotlighted as a simple, fast process, cost-effective, eco-friendly route, high yield, high product purity, and easily reproducible for various applications [ 15 , 16 ]. One of the main advantages of this method is that it can directly obtain water-soluble nanoparticles without requiring hazardous organic solvents or treatments under high pressure or temperature.…”

Section: Introductionmentioning

confidence: 99%

Formulation and Characterization of Fe3O4@PEG Nanoparticles Loaded Sorafenib; Molecular Studies and Evaluation of Cytotoxicity in Liver Cancer Cell Lines

et al. 2023

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Iron oxide nanoparticles are one of the nanocarriers that are suitable for novel drug delivery systems due to low toxicity, biocompatibility, loading capacity, and controlled drug delivery to cancer cells. The purpose of the present study is the synthesis of coated iron oxide nanoparticles for the delivery of sorafenib (SFB) and its effects on cancer cells. In this study, Fe3O4 nanoparticles were synthesized by the co-precipitation method, and then sorafenib was loaded onto PEG@Fe3O4 nanoparticles. FTIR was used to ensure polyethylene glycol (PEG) binding to nanoparticles and loading the drug onto the nanoshells. A comparison of the mean size and the crystalline structure of nanoparticles was performed by TEM, DLS, and X-ray diffraction patterns. Then, cell viability was obtained by the MTT assay for 3T3 and HepG2 cell lines. According to FT-IR results, the presence of O–H and C–H bands at 3427 cm–1 and 1420 cm–1 peak correlate with PEG binding to nanoparticles. XRD pattern showed the cubic spinel structure of trapped magnetite nanoparticles carrying medium. The magnetic properties of nanoparticles were examined by a vibrating-sample magnetometer (VSM). IC50 values at 72 h for treatment with carriers of Fe3O4@PEG nanoparticle for the HepG2 cell line was 15.78 μg/mL (p < 0.05). This study showed that Fe3O4 nanoparticles coated by polyethylene glycol and using them in the drug delivery process could be beneficial for increasing the effect of sorafenib on cancer cells.

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Magnetite Nanoparticles: Synthesis and Applications in Optics and Nanophotonics

Cited by 53 publications

References 130 publications

Approaches for neutrophil imaging: an important step in personalized medicine

Approaches for neutrophil imaging: an important step in personalized medicine

Insights into the Magnetic Properties of Single-Core and Multicore Magnetite and Manganese-Doped Magnetite Nanoparticles

Formulation and Characterization of Fe3O4@PEG Nanoparticles Loaded Sorafenib; Molecular Studies and Evaluation of Cytotoxicity in Liver Cancer Cell Lines

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