Magnetization transfer imaging of the abdomen at 0.1 T: Detection of hepatic neoplasms

Kahn, Charles Η.; Perera, Saman; Sepponen, Raimo; Tanttu, Jukka I.; Tierala, E.; Lipton, Martin J.

doi:10.1016/0730-725x(93)90413-8

Cited by 18 publications

(5 citation statements)

References 10 publications

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“…A lack of consensus seems to exist in the literature concerning the diagnostic ability of MTC to detect lesion contrast in liver diseases (8)(9)(10)18,24). We believe the reason for this is that MTC is an complicated subject and many related issues needed to be examined before a coherent picture emerges.…”

Section: Discussionmentioning

confidence: 80%

“…Regarding the diagnostic ability of MTC in hepatic lesion contrast, previous studies (8)(9)(10) showed no consensus on why lesion enhancement was not improved, nor were the reasons for this failure discussed. Basically, lesion contrast in MRI reflects the relative signal intensity of the lesion and the background tissue.…”

Section: Discussionmentioning

confidence: 93%

“…Consequently, the effort is warranted to determine the optimal RF pulse train that would yield the best contrast. Finally, it is worth noting that most of the previous studies in the literature (8)(9)(10)18) focused on hepatic tumors only. In this study, patients with diffuse liver diseases such as fatty liver, chronic hepatitis, and cirrhosis were also included.…”

mentioning

confidence: 98%

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Evaluation of liver diseases via MTC and contrast agent

Chen

Yeung

Lee

et al. 1999

J. Magn. Reson. Imaging

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Section: Discussionmentioning

confidence: 80%

Section: Discussionmentioning

confidence: 93%

mentioning

confidence: 98%

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Evaluation of liver diseases via MTC and contrast agent

Chen

Yeung

Lee

et al. 1999

J. Magn. Reson. Imaging

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“…In a study with low field strength (0.1 T) a significant but not as remarkable increase in brain tumor CNR was found with combined use of MT and Gd-DTPA (Abo Ramadan et al 1997). Using the background suppression capability MT technique has been exploited in MR angiography (Edelman et al 1992,) and also for contrast improvement in liver neoplasms (Outwater et al 1992, Kahn et al 1993, Halavaara et al 1998, breast (Flamig et al 1992), normal knee (Wolf et al 1991) and heart ).…”

Section: Tissue Characterization Of Head and Neck And Brain Tumors Wimentioning

confidence: 99%

Spin lock and magnetization transfer imaging of head and neck tumors.

Markkola¹,

Aronen²,

Paavonen³

et al. 1996

Radiology

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“…One of the new approaches for tissue characterization in MRI is magnetization transfer (MT) imaging (3,4). This imaging technique has potential utility in several applications (5)(6)(7)(8)(9). 18) but the results have been partly contradictory (16).…”

Section: Introductionmentioning

confidence: 99%

Improvement of brain lesion detection at 0.1 T by simultaneous use of Gd‐DTPA and magnetization transfer imaging

Ramadan

Aronen

Tanttu³

et al. 1997

Magnetic Resonance in Med

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Imaging parameters were optimized at 0.1 T to improve contrast-to-noise ratios (CNR) when combining magnetization transfer (MT) imaging and the use of paramagnetic contrast medium. This was accomplished by imaging a phantom containing serial concentrations of Gd-DTPA in cross-linked bovine serum albumin. With the use of simulations, the dependence of CNR on imaging parameters was studied. Conventional and MT images were obtained from 10 brain tumor patients with single and triple doses of Gd-DTPA. Simulations demonstrated the importance of TR in postcontrast sequences. The CNR in MT images is less sensitive to TR than in conventional images. A significant CNR improvement caused by MT remains at longer TR when there is no contrast enhancement without MT. The clinical results indicate that a single dose of Gd-DTPA combined with MT cannot replace imaging with a triple dose. However, MT significantly improved the CNR after single and triple Gd-DTPA-doses on T1-weighted and proton-density images.

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Magnetization transfer imaging of the abdomen at 0.1 T: Detection of hepatic neoplasms

Cited by 18 publications

References 10 publications

Evaluation of liver diseases via MTC and contrast agent

Evaluation of liver diseases via MTC and contrast agent

Spin lock and magnetization transfer imaging of head and neck tumors.

Improvement of brain lesion detection at 0.1 T by simultaneous use of Gd‐DTPA and magnetization transfer imaging

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