A low-temperature synthesis of novel nanostructured CoxNi1-xMn0.5Fe1.5O4(x=0,0.25,0.5,0.75,1) ferrites was carried out by sol-gel auto-combustion technique. The obtained nanostructured ferrites were investigated by employing the techniques of powder X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), energy dispersive X-ray spectroscopy (EDX) and vibrating sample magnetometry (VSM). The XRD diffractograms of the prepared ferrites revealed the formation of a spinel phase with face centered cubic (fcc) structure belonging to Fd- m space group. The average lattice parameter ‘a’ of ferrites exhibited a rise versus a rise in Co2+ concentration in accordance with the Vegard’s law. The SEM investigation of NiMn0.5Fe1.5O4 powder revealed an existence of octahedral-shaped morphology of ferrite grains. The TEM investigation of NiMn0.5Fe1.5O4 powder showed nanostructures of ferrite particles with sizes consistent with the crystallite sizes as estimated by Debye-Scherer’s formula. An EDX spectrum of NiMn0.5Fe1.5O4 powder confirmed its elemental composition. The M-H hysteresis loops recorded by VSM at room temperature revealed a dependence of coercivity (Hc), maximum magnetization (Mmax) and retentivity (Mr) on Co2+concentration. Due to the shape dependence of M-H loops on Co2+ concentration in compounds enabled their candidature for applications in memory devices and magnetic sensors.