Magnetoimpedance Biosensors and Real-Time Healthcare Monitors: Progress, Opportunities, and Challenges

Jimenez, Valery Ortiz; Hwang, Kee Young; Nguyen, Dang Trang; Rahman, Yasif; Albrecht, Claire; Senator, Baylee; Thiabgoh, O.; Devkota, Jagannath; Bui, Vinh Duc An; Lam, Dao Son; Eggers, Tatiana; Phan, Manh‐Huong

doi:10.3390/bios12070517

Cited by 28 publications

(8 citation statements)

References 100 publications

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“…[110,111] The MLCR design draws inspiration from conventional magneto-inductive coils and the sensitivity of the giant magneto-impedance (GMI) effect, [112] which has proven useful for detecting ultra-small magnetic fields in biosensing applications and for structural health monitoring. [113,114] The sensor is constructed from a Co-rich soft magnetic microwire exhibiting very high GMI ratios and magnetic field sensitivity. The melt-extracted amorphous microwire, with a nominal composition of Co 69.25 Fe 4.25 Si 13 B 12.5 Nb 1 and diameter of approximately 60 μm, is wound into a 15-turn, 10-mm-long coil with a 5 mm internal diameter.…”

Section: Magneto-lc Resonance Magnetometry For Probing Light-mediated...mentioning

confidence: 99%

Transition Metal Dichalcogenides: Making Atomic‐Level Magnetism Tunable with Light at Room Temperature

Ortiz Jimenez,

Pham,

Zhou

et al. 2023

Advanced Science

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The capacity to manipulate magnetization in 2D dilute magnetic semiconductors (2D‐DMSs) using light, specifically in magnetically doped transition metal dichalcogenide (TMD) monolayers (M‐doped TX2, where M = V, Fe, and Cr; T = W, Mo; X = S, Se, and Te), may lead to innovative applications in spintronics, spin‐caloritronics, valleytronics, and quantum computation. This Perspective paper explores the mediation of magnetization by light under ambient conditions in 2D‐TMD DMSs and heterostructures. By combining magneto‐LC resonance (MLCR) experiments with density functional theory (DFT) calculations, we show that the magnetization can be enhanced using light in V‐doped TMD monolayers (e.g., V‐WS2, V‐WSe2). This phenomenon is attributed to excess holes in the conduction and valence bands, and carriers trapped in magnetic doping states, mediating the magnetization of the semiconducting layer. In 2D‐TMD heterostructures (VSe2/WS2, VSe2/MoS2), the significance of proximity, charge‐transfer, and confinement effects in amplifying light‐mediated magnetism is demonstrated. We attributed this to photon absorption at the TMD layer that generates electron–hole pairs mediating the magnetization of the heterostructure. These findings will encourage further research in the field of 2D magnetism and establish a novel design of 2D‐TMDs and heterostructures with optically tunable magnetic functionalities, paving the way for next‐generation magneto‐optic nanodevices.

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Section: Magneto-lc Resonance Magnetometry For Probing Light-mediated...mentioning

confidence: 99%

Transition Metal Dichalcogenides: Making Atomic‐Level Magnetism Tunable with Light at Room Temperature

Ortiz Jimenez,

Pham,

Zhou

et al. 2023

Advanced Science

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“…The superiority of the wet etching process is the high efficiency for batch production of ribbon-based sensors with consistent performance (Zhen et al, 2020). Meanwhile, the batch ribbons can be integrated with a microfluidic platform to obtain accordant magnetic biochips (Feng et al, 2019b;Jimenez et al, 2022). Therefore, obtaining microribbon with meander type by wet etching has become an important method in the application of GMI sensing.…”

Section: Introductionmentioning

confidence: 99%

“…Meanwhile, the batch ribbons can be integrated with a microfluidic platform to obtain accordant magnetic biochips (Feng et al. , 2019b; Jimenez et al. , 2022).…”

Section: Introductionmentioning

confidence: 99%

Line spacing effect on the giant magnetoimpedance behavior on microribbon with meander type: a comparison of theory and experiment

Wang,

Yang,

Liu

et al. 2024

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Purpose Microribbon with meander type based on giant magnetoimpedance (GMI) effect has become a research hot spot due to their higher sensitivity and spatial resolution. The purpose of this paper is to further optimize the line spacing to improve the performance of meanders for sensor application. Design/methodology/approach The model of GMI effect of microribbon with meander type is established. The effect of line spacing (Ls) on GMI behavior in meanders is analyzed systematically. Findings Comparison of theory and experiment indicates that decreasing the line spacing increases the negative mutual inductance and a consequent increase in the GMI effect. The maximum value of the GMI ratio increases from 69% to 91.8% (simulation results) and 16.9% to 51.4% (experimental results) when the line spacing is reduced from 400 to 50 µm. The contribution of line spacing versus line width to the GMI ratio of microribbon with meander type was contrasted. This behavior of the GMI ratio is dominated by the overall negative contribution of the mutual inductance. Originality/value This paper explores the effect of line spacing on the GMI ratio of meander type by comparing the simulation results with the experimental results. The superior line spacing is found in the identical sensing area. The findings will contribute to the design of high-performance micropatterned ribbon with meander-type GMI sensors and the establishment of a ribbon-based magnetic-sensitive biosensing system.

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“…Detection of small magnetic particle is important for avoiding a contamination of industrial and chemical products. It is also important for detecting magnetic nano-particles included in cells and biomolecules for medical and healthcare technology [1].…”

Section: Introductionmentioning

confidence: 99%

Study on Detection of a Small Magnetic Particle Using Thin Film Magneto-Impedance Sensor with Subjecting to Strong Normal Field

Nakai

2022

Micromachines

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This paper deals with the detection of small magnetization using a thin film magneto-impedance sensor with subjecting to strong normal field. The sensor was made by soft magnetic amorphous thin-film with uniaxial magnetic anisotropy in the width direction of the element. It was reported that the sensor has very high sensitivity, such as pico-tesla order, when it is driven by hundreds of MHz. In this paper, a sensitive measurement method aiming for detection of a small particle or a cluster of nano-particles, having low-remanence, is proposed. The point is the application of strong normal field in the measurement area including sensor element and particle. The normal strong field is applied in the normal direction of the sensor plane in the value almost hundreds of mT. Instead of such strong normal field, the sensor keeps high sensitivity, because of the demagnetizing force in the thickness direction. A theoretical estimation for clarifying an efficiency of the method, experimental results of sensor property and sensitivity with subjecting to the normal field, and also a confirmation of detection of a small particle using the proposed method is reported. As a special mention, detection fundamentals when a applied surface normal field has a distribution and also a particle would run through in the vicinity of sensor is discussed.

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Magnetoimpedance Biosensors and Real-Time Healthcare Monitors: Progress, Opportunities, and Challenges

Cited by 28 publications

References 100 publications

Transition Metal Dichalcogenides: Making Atomic‐Level Magnetism Tunable with Light at Room Temperature

Transition Metal Dichalcogenides: Making Atomic‐Level Magnetism Tunable with Light at Room Temperature

Line spacing effect on the giant magnetoimpedance behavior on microribbon with meander type: a comparison of theory and experiment

Study on Detection of a Small Magnetic Particle Using Thin Film Magneto-Impedance Sensor with Subjecting to Strong Normal Field

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