Main reasons for hospital admission in patients with ParkinsonÓ?s disease and their relationship with the days of hospitalization

Abstract

Objective: It is necessary to study the main comorbidities of Parkinson's disease that causes this increase in hospitalization.The aim of the study was to compare the mean days of hospital stay of patients with Parkinson's disease plus a comorbidity against the mean days of hospital stay without that comorbidity and to report those which were statistically significant. Methods: Taking patients with PD from "1 de octubre" Hospital, an observational, retrospective, cross-sectional, and analytical study was carried out in which the relationship of days of hospitalization with and without comorbidities was evaluated, finding which would be the comorbidities that were they become a factor of protection or risk of prolonging the hospital stay of patients with Parkinson's disease (PD) and thus suggest the priority of treating these conditions. Results: Of the 37 patients, 14 different comorbidities were found, of which hypothyroidism ( x = 2), acute myocardial infarction/dyslipidemia ( x = 4), and traumatic brain injury ( x = 4) present a decrease in the number of days hospitalized patients with respect to the mean of patients who do not have these comorbidities, in comparison, sacral ulcer ( x = 32.5) and pneumonia ( x = 31) show an increase in the days of hospitalization with respect to the mean. Conclusion: Fourteen comorbidities were found in PD. Patients with sacral ulcer and pneumonia are hospitalized for a longer time compared to the different comorbidities. It is recommended to pay special attention and care to prevent/treat these pathologies to reduce the number of days of hospitalization.

Neuroinflammation in Parkinson’s Disease: From Gene to Clinic: A Systematic Review

“…Given the above, the complexity of the clinical manifestations and the interactions between the molecular, cellular and physiological pathways leads to challenges in the therapeutic management of patients; therefore, a new perspective that has been developed with the advancement of bioinformatic tools is the generation of polypharmacological strategies, which represent a viable alternative to explore in the future [ 119 , 120 , 121 ].…”