Maintenance Breeding

Yadav, Ram Naresh; Kumar, Priya Ranjan; Hussain, Zakir; Yadav, Sangita; Lal, S. K.; Kumar, Atul; Singh, Pramod Kumar; Bera, Amit; Yadav, Shiv Kumar

doi:10.1007/978-981-16-9257-4_13

Cited by 7 publications

(9 citation statements)

References 11 publications

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“…Monika Yadav et al [112] . developed a protocol for synthesis of a new series of indole‐chalcone linked 1,2,3‐triazole derivatives 542 (a–b) and 544 (a–j) .…”

Section: Chemistry Of Indole Based Heterocycle Scaffoldsmentioning

confidence: 99%

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Bendi,

Versha,

Rajni

et al. 2023

ChemistrySelect

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The importance of indole‐based heterocycle scaffolds in medicinal chemistry has increased as a result of their significant pharmacological and biological characteristics. These compounds′ importance in the discovery and creation of cutting‐edge medications to treat a variety of diseases is an instance of their worth. The current study highlights the numerous methods available to create different indole‐based heterocycle scaffolds and their favourable medical uses with the literature that has been published up to 2023.

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“…Monika Yadav et al [112] . developed a protocol for synthesis of a new series of indole‐chalcone linked 1,2,3‐triazole derivatives 542 (a–b) and 544 (a–j) .…”

Section: Chemistry Of Indole Based Heterocycle Scaffoldsmentioning

confidence: 99%

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Bendi,

Versha,

Rajni

et al. 2023

ChemistrySelect

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“…[A] 2007) about 42 rice varieties, through MAS and MABB using molecular markers, have been developed carrying different genes and their combination characterising various agronomic and disease resistance genes (Yadav et al 2022).…”

Section: Marker-assisted Breedingmentioning

confidence: 99%

“…Later on, PBW343 was introgressed with Aegilops umbellulata-derived genes, Yr40 and Yr57 and Aegilops ventricosa-derived linked genes Yr17, Lr37, Sr38. This led to the development of Improved varieties PBW 723 (Yr17, Yr40, Lr57) and PBW 771 (Yr40 and Lr57) using marker assisted backcross breeding (Yadav et al 2022). Very recently, two varieties namely, Unnat HD 2967 and Unnat HD 2932 have been identified for release.…”

Section: Cerealsmentioning

confidence: 99%

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Recent trends in crop breeding, the varietal induction in seed chain and its impact on food grain production in India

Singh

Chauhan

Choudhury

et al. 2022

IJGPB

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Food grains in India achieved an all-time high production (310.74 mt) during 2020-21. Varietal and seed replacement rates played an important role in achieving this milestone. A total of 1646 varieties of food crops comprising 1273 of cereals and 373 of pulses were released from 2011 to 2022. Of these 977 varieties consisting of cereals (667) and pulses (310) have been inducted into the seed chain during 2020-21. New breeding technonologies such as bio-fortification of food crops and marker-assisted breeding were applied to improve crop varieties with respect to specific desirable traits. A total of 65 bio-fortified varieties comprising rice (8), wheat (28), maize (14), pearl millet (9), finger millet (3), little millet (1) and lentil (2) have been released with improved levels of proteins, essential amino acids (lysine, tryptophan), vitamins (pro-vitamin A) and micro/macro-nutrients (zinc, iron, calcium). Marker-assisted breeding adopting foreground and background selections with targeted gene(s) utilizing molecular markers such as RFLPs, SSRs, CAPs, STS and INDEL resulted in to the development and release of 66 cultivars comprising rice (43), wheat (5), maize (10), pearl millet (2) and chickpea (6) with one/and or combination of traits such as tolerance to biotic/abiotic stresses, herbicide tolerance, nutrient use efficiency, earliness, nutritional and other quality traits. These non-genetically modified crop varieties are expected to play vital role in achieving food and nutrition security in India. The paper also provides insight in to the maintenance breeding of food crops. The analysis of seed requirement and availability during 2010-11 to 2020-21 revealed that seed requirements for cereals and pulses have increased consistently by 31.6% and 62.3%, from 186.8 to 245.8 lakh q and 22.3 to 36.2 lakh q, respectively. The production of rice, wheat, maize, pearl millet and pulses during 2020-21 increased over that of 2010-11 by 27.4%, 26.0%, 45.2%, 4.4% and 41.3%, respectively. The productivity of sorghum was higher by 18.9% over that of 2010-11 but production decreased by 31.7% on account of a reduction in acreage by 42.5% during the corresponding period. The net per capita availability of food grains increased, by 17.2% from 159.5 kg to 187.0 kg during this period. The cereals and pulses production needs to be up-scaled by 5.3% and 24.4% to meet the demand by 2030 from 285.28 mt and 25.46 mt, respectively, in 2020-21, with almost the similar acreage, degrading and depleting natural resources, thus, requiring a greater focus on enhancing yield/ha. Crop-specific breeding programmes should be accelerated with the adoption of new technologies like GM, gene editing, marker-assisted selection and speed breeding to address the challenges of climate change and degrading natural sources.

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“…Kamel et al displayed potent antibacterial activity against B. mycoides and E. coli and antifungal activity against C. albicans [29] . Majority of the indole‐chalcone tethered 1,2,3‐triazole derivatives developed by M. Yadav et al exhibited excellent potency against the tested bacterial and fungal strains [30] . Further, M. Asad's group synthesized the chromonyl chalcone hybrids via green approach revealed to be highly potent antibacterial and antifungal agents [31]…”

Section: Introductionmentioning

confidence: 99%

Design, Synthesis, Antimicrobial Screening and Docking Studies of Newer 1,4‐Dihydropyridine tethered Chalcone Hybrids

Kumar¹,

Kumar

Upadhyay³

et al. 2022

ChemistrySelect

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The evolution of antimicrobial drug resistance demands the development of more effective therapeutics that are more potent with reduced side effects. In the present study, we reported the design and synthesis of 1,4-dihydropyridine clubbed with chalcone hybrids in excellent yields. Further, the biological assessment of these 1-phenyl-3-dihydropyridineprop-2-en-one chalcone hybrids as antimicrobial agents was accomplished against strains E.coli, Klebsiella pneumonia, Salmonella typhi, Staphylococcus aureus, Candida albicans (Yeast), Aspergillus niger, Alternaria solani and Fusarium oxy-sporum by well diffusion method in terms of zone of inhibition (in mm). Some Hybrids displayed the best anti-microbial activity against all the tested strains. A molecular docking study was performed for the most active compounds and showed the best binding pose with the highest binding score within the active sites of S. aureus DNA gyrase complexed with DNA and Lanosterol 14α-demethylase. These novel products evolved as promising leads for the future development of more potent anti-microbial compounds.

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Maintenance Breeding

Cited by 7 publications

References 11 publications

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Insight into Indole‐Based Heterocyclic Scaffolds: A Medicinal Chemistry Perspective

Recent trends in crop breeding, the varietal induction in seed chain and its impact on food grain production in India

Design, Synthesis, Antimicrobial Screening and Docking Studies of Newer 1,4‐Dihydropyridine tethered Chalcone Hybrids

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