Major electrocardiographic abnormalities among American Indians aged 45 to 74 years (the strong heart study)

Oopik, Arvo J.; Dorogy, Mark E.; Devereux, Richard B.; Yeh, Jeun Liang; Okin, Peter M.; Lee, Elisa T.; Cowan, Linda D.; Fabsitz, Richard R.; Howard, Barbara V.; Welty, Thomas K.

doi:10.1016/s0002-9149(96)00642-x

Cited by 24 publications

(12 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The Strong Heart Study data showed high insulin concentrations, high waisthip ratios, and the typical dyslipidemia characterized by elevated triglycerides; low HDL; and small, dense LDL particles. 6,24 In the present data, the univariate analysis showed that plasma insulin concentration was a significant correlate in men, triglycerides were significant in women, and HDL had a strong inverse association in both men and women. In the proportional hazards model, neither insulin nor HDL remained significant, and triglyceride was a significant predictor only in women.…”

Section: Discussionsupporting

confidence: 55%

“…The present longitudinal analysis was undertaken to clarify the apparent discrepancy between the initial cross-sectional data 2,6 and subsequent reports 7 on CVD prevalence and mortality in the Strong Heart Study. The present data showed that whereas incidence rates for nonfatal CVD in Arizona men were lower than those in Oklahoma and South/North Dakota, incidence rates for nonfatal CVD in women and CVD mortality in both men and women were similar in all 3 centers.…”

Section: Discussionmentioning

confidence: 98%

“…Prevalence data from the initial examination suggested that American Indians had somewhat lower rates of myocardial infarction (MI) and CHD than other US groups 2,6 and a lower prevalence of MI and CHD in certain Arizona Indians compared with those in South/North Dakota or Oklahoma. A 1984 to 1988 mortality survey, however, showed fewer differences in CVD mortality rates among geographic areas.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Rising Tide of Cardiovascular Disease in American Indians

et al. 1999

Self Cite

View full text Add to dashboard Cite

Background-Although cardiovascular disease (CVD) used to be rare among American Indians, Indian Health Service data suggest that CVD mortality rates vary greatly among American Indian communities and appear to be increasing. The Strong Heart Study was initiated to investigate CVD and its risk factors in American Indians in 13 communities in Arizona, Oklahoma, and South/North Dakota. Methods and Results-A total of 4549 participants (1846 men and 2703 women 45 to 74 years old) who were seen at the baseline (1989 to 1991) examination were subjected to surveillance (average 4.2 years, 1991 to 1995), and 88% of those remaining alive underwent a second examination (1993 to 1995). The medical records of all participants were exhaustively reviewed to ascertain nonfatal cardiovascular events that occurred since the baseline examination or to definitively determine cause of death. CVD morbidity and mortality rates were higher in men than in women and were similar in the 3 geographic areas. Coronary heart disease (CHD) incidence rates among American Indian men and women were almost 2-fold higher than those in the Atherosclerosis Risk in Communities Study. Significant independent predictors of CVD in women were diabetes, age, obesity (inverse), LDL cholesterol, albuminuria, triglycerides, and hypertension. In men, diabetes, age, LDL cholesterol, albuminuria, and hypertension were independent predictors of CVD. Conclusions-At present, CHD rates in American Indians exceed rates in other US populations and may more often be fatal. Unlike other ethnic groups, American Indians appear to have an increasing incidence of CHD, possibly related to the high prevalence of diabetes. In the general US population, the rising prevalence of obesity and diabetes may reverse the decline in CVD death rates. Therefore, aggressive programs to control diabetes and its risk factors are needed.

show abstract

Section: Discussionsupporting

confidence: 55%

Section: Discussionmentioning

confidence: 98%

mentioning

confidence: 99%

See 1 more Smart Citation

Rising Tide of Cardiovascular Disease in American Indians

et al. 1999

Self Cite

View full text Add to dashboard Cite

show abstract

“…Fatal and nonfatal cardiovascular events, including MI, stroke, coronary heart disease, and heart failure, were identified from sources in each community and through annual follow-up of participants and verified through death certificates and review of medical records, as described previously. 8,15 An independent review panel of physicians who were blinded to echocardiographic data adjudicated deaths as cardiovascular if caused by MI, stroke, sudden death due to definite coronary heart disease, 11,15,16 or CHF. 17 Similarly, medical records were reviewed by an expert physician panel to identify nonfatal cardiovascular events that occurred after the second SHS examination.…”

Section: Clinical End Pointsmentioning

confidence: 99%

“…Prevalent coronary heart disease was diagnosed by self-report at the first SHS examination or on the basis of subsequent MI, confirmed by a physician-comprised morbidity committee (blinded to echocardiographic data), coronary angiographic documentation of major epicardial coronary artery obstruction, PTCA, coronary bypass, or major Q-wave Minnesota codes for MI 11,15,16 ; CHF was identified by Framingham Heart Study criteria, 17 as described previously. 8,15 Echocardiography All echocardiograms were evaluated at a central reading center (Weill Cornell Medical Center, New York, NY).…”

mentioning

confidence: 99%

Prevalence and Prognostic Significance of Wall-Motion Abnormalities in Adults Without Clinically Recognized Cardiovascular Disease

et al. 2007

Self Cite

View full text Add to dashboard Cite

Background-Left ventricular wall motion (WM) abnormalities have recognized prognostic significance in patients with coronary or other heart diseases; however, whether abnormal WM predicts adverse events in adults without overt cardiovascular disease has not been assessed. Our objective was to determine whether echocardiographic WM abnormalities predict subsequent cardiovascular events in a population-based sample. Methods and Results-Participants (nϭ2864, mean age 60Ϯ8 years, 64% women) without clinically evident cardiovascular disease in the second Strong Heart Study examination who had complete echocardiographic WM assessment were studied. Echocardiographic assessment revealed that 5% of participants (nϭ140) had focal hypokinesia, and 1.5% (nϭ42) had WM abnormalities. Relationships between WM abnormalities and fatal and nonfatal cardiovascular events (including myocardial infarction, stroke, coronary artery disease, and heart failure; nϭ554) and cardiovascular death (nϭ182) during 8Ϯ2 years follow-up were examined. In Cox regression, after adjustment for age, gender, waist/hip ratio, systolic blood pressure, and diabetes mellitus, segmental WM abnormalities were associated with a 2.5-fold higher risk of cardiovascular events and a 2.6-fold higher risk of cardiovascular death (both PϽ0.0001). In similar multivariable models, global WM abnormalities were associated with a 2.4-fold higher risk of cardiovascular events (Pϭ0.001) and a 3.4-fold higher risk of cardiovascular death (Pϭ0.003). Conclusions-Echocardiographic

show abstract

Electrocardiographic T Wave Changes in Left Ventricular Hypertrophy

Franz¹

2004

Dynamic Electrocardiography

View full text Add to dashboard Cite

Major electrocardiographic abnormalities among American Indians aged 45 to 74 years (the strong heart study)

Cited by 24 publications

References 16 publications

Rising Tide of Cardiovascular Disease in American Indians

Rising Tide of Cardiovascular Disease in American Indians

Prevalence and Prognostic Significance of Wall-Motion Abnormalities in Adults Without Clinically Recognized Cardiovascular Disease

Electrocardiographic T Wave Changes in Left Ventricular Hypertrophy

Contact Info

Product

Resources

About