Major geometric variations between multiple high-dose-rate applications of brachytherapy in cancer of the cervix: frequency and types of variation.

Abstract

Awareness of geometric variations should improve proper placement of intracavitary applicators for brachytherapy.

Image-based three-dimensional treatment planning of intracavitary brachytherapy for cancer of the cervix: Dose-volume histograms of the bladder, rectum, sigmoid colon, and small bowel

“…Although most of these factors associated with complications inherent to the patients are not subject to modification, the radiation dose given to OARs can be controlled to some extent. Therefore, optimal geometry of the applicator has been emphasized (11,12).…”

Factors for Predicting Rectal Dose of High-Dose-Rate Intracavitary Brachytherapy After Pelvic Irradiation in Patients With Cervical Cancer: A Retrospective Study With Radiography-Based Dosimetry

“…However, there was no evidence of a doseÀvolume effect on rectal complications using CT-based dosimetry. Hence, radiography-based (20)(21)(22); the causes include slippage (tandem and colpostats), inadequate separation of the colpostats, axis deviation, and inadequate posterior vaginal packing (20). Extent of vaginal packing influences the ICRU rectal dose (9); the compliance of the vaginal wall may determine the extent of packing.…”

Assessment of Tumor Regression by Consecutive Pelvic Magnetic Resonance Imaging and Dose Modification during High-Dose-Rate Brachytherapy for Carcinoma of the Uterine Cervix

“…During multiple fractionated HDR-BT, it is known that the position of the BT applicators may change (13,14). In addition, further continuous tumor regression and resultant anatomical changes may also occur, especially during multi-fractionated HDR-BT.…”