Major Hematological Diseases Associated With Cleft Lip and Palate

Lin, Cheng–Hui; Lo, Lun-Jou; Wang, Min-Lun; Chen, Yu-Ray; Noordhoff, M. Samuel

doi:10.1597/1545-1569(2000)037<0512:mhdawc>2.0.co;2

Cited by 6 publications

(4 citation statements)

References 10 publications

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“…In this study the secondary alveolar cleft grafting technique was carried out between 7 and 12 years ago, and this is in agreement with Lin C et al 28 , who stated that, this age is the most suitable timing for residual alveolar cleft grafting to avoid the detrimental effects on the transverse growth of the maxilla which is nearly completed by about the 6 or 7 years of age.…”

Section: Discussionsupporting

confidence: 86%

Sonic Weld Biodegradable Plating System for Bone Graft Fixation in Alveolar Cleft Repair

Nowair

2017

Egyptian Dental Journal

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Cleft lip and/or palate is the most widely known congenital malformation of the orofacial region. Secondary bone grafting of alveolar clefts combined with subsequent orthodontic treatment, designed to obtain a nonprosthodontic dental rehabilitation and also eliminate the other deficiencies attributable to the osseous defect. This study aimed to evaluate the role of graft fixation by using sonic weld biodegradable plating system on alveolar cleft repair Patients and methods Ten patients with unilateral alveolar clefts ( right and left) were included in this study. The patients were evaluated with age ranging between (7-12) years. They were treated by secondary grafting procedures of their alveolar clefts using chin bone block fitted in the cleft and fixed by sonic weld biodegradable bone plates. The patients were followed up for 6 months both clinically and radiographically Results: Uneventful soft tissue healing regarding soft tissue wounds. The alar base was augmented for all patients and the soft tissue scar had been matured (no tenderness) by about the third month postoperatively. The postoperative radiological results were excellent in all patients, regarding the alveolar bone height bordering the teeth mesially and distally, the incorporation of the graft material with the surrounding bone or the degree of eruption of the cleft related permanent teeth (lateral and canine) through the graft. Conclusion:By the end of this study the author concluded that the fixation of monoblock corticocancellous bone graft in alveolar cleft repair using sonic weld plating system is useful as it maintain the graft volume and height.

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Section: Discussionsupporting

confidence: 86%

Sonic Weld Biodegradable Plating System for Bone Graft Fixation in Alveolar Cleft Repair

Nowair

2017

Egyptian Dental Journal

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“…Eosinophilia and lots of patients with eosinophil count close to higher normal limits were seen and was probably due to local climatic factors and co-incidental worm infestation or allergy which can be attributed to this geographical region where allergies are common. [ 7 28 ] Absolute eosinophil count (AEC) was therefore considered to be a more suitable parameter in these patients for evaluation of these specific granulocytes. Whatever the reason, the raised values are significant and it delays the surgical management by 5–7 days, which again is unaffordable by these poverty stricken patients and their attendants.…”

Section: Discussionmentioning

confidence: 99%

A clinical and demographic profile of the cleft lip and palate in Sub-Himalayan India: A hospital-based study

Dvivedi

2012

Indian J Plast Surg

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Objectives:To study the cleft lip and cleft palate in the poverty stricken Sub-Himalayan Garhwal region of India, being a commonly seen congenital abnormality and scarcity of studies about the demography of cleft in this region.Design:A prospective cohort observational case series was performed on 4657 cleft patients at a Tertiary care Hospital in Dehradun, India, over a period of 5 years.Outcome measures:The authors investigated the differences between age and sex with cleft status and family history of clefts, birth order, religion, socioeconomic status, parent literacy, source of information for treatment, haematological investigations showing the status of infection and coagulation in such children and satisfaction after treatment.Results:Seventy-two percent parents of cleft lip patients were illiterate, and only 8% were graduates, the majority of patients were from the low socioeconomic class. The siblings of 1.1% of the cleft patients had similar deformity. Anemia was seen in 83.16% cases which was commonly microcytic hypochromic type and eosinophilia was seen in 25.50% of cases. In the coagulation profile, International Nationalized Ratio was found to be raised in 52.12%. Almost 95% of the families were fully satisfied by the treatment and results.Conclusion:This study will provide baseline information on the status of these less privileged cleft patients in this mountainous region for future reference to health workers.

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“…It is demonstrated that operative procedures in appropriately prepared patients with blood disorder are not associated with a high mortality rate (Lin et al, 2000). In this case, we decided to operate after consulting with the anesthetist and hematologist.…”

Section: Discussionmentioning

confidence: 99%

“…An association of cleft lip, palate, or both with other congenital anomalies or syndromes is not unusual with reported frequencies ranging from 6% to 63% (Shprintzen et al, 1985). However, the combination of cleft lip and palate with blood disorders has been rarely reported, probably due to the rarity of such coexisting conditions (Lin et al, 2000). Here, we report a case of cleft lip, alveolus, and palate associated with cyclic neutropenia.…”

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confidence: 99%

Cyclic Neutropenia in a Cleft Lip and Palate Patient: A Case Report

Desai¹,

Gopalkrishnan²,

Joshi³

et al. 2011

The Cleft Palate Craniofacial Journal

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Cleft lip and palate is the most common congenital anomaly. Its association with hematologic disorders is rarely reported. Cyclic neutropenia is a rare blood disorder that may occur spontaneously or has a genetic predisposition. Periodicity/recurrence of cyclic neutropenia has a cyclical pattern reoccurring in multiples of 7 days, usually at 21- or 28-day intervals between attacks, with the patient being fairly asymptomatic. There is no case in the literature that has reported the presence of cyclic neutropenia in cleft patients. We report a case of cleft patient associated with cyclic neutropenia. The clinical features, diagnosis, and course of management are described.

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Major Hematological Diseases Associated With Cleft Lip and Palate

Abstract: Association of major hematological disorders and cleft lip, palate, or both is rare and is reported herein.

Cited by 6 publications

References 10 publications

Sonic Weld Biodegradable Plating System for Bone Graft Fixation in Alveolar Cleft Repair

Sonic Weld Biodegradable Plating System for Bone Graft Fixation in Alveolar Cleft Repair

A clinical and demographic profile of the cleft lip and palate in Sub-Himalayan India: A hospital-based study

Cyclic Neutropenia in a Cleft Lip and Palate Patient: A Case Report

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