Makeshift hospitals for COVID-19 patients: where health-care workers and patients need sufficient ventilation for more protection

Chen, Chen; Zhao, Bin

doi:10.1016/j.jhin.2020.03.008

Cited by 78 publications

(72 citation statements)

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“…by using movable walls ( Carra and Magdani, 2017 ). Insufficient ventilation can increase the risk of infection to healthcare workers and susceptible patients in healthcare buildings, especially makeshift hospitals ( Chen and Zhao, 2020 ). The impact of these engineering measures on energy consumption of typical buildings and healthcare facilities needs to be considered because of social distancing measures, which may require a decrease in occupant density but an increase in ventilation rates.…”

Section: Opportunities For Circular Economy Post Covid-19mentioning

confidence: 99%

A critical analysis of the impacts of COVID-19 on the global economy and ecosystems and opportunities for circular economy strategies

Ibn‐Mohammed

Mustapha

Godsell

et al. 2021

Resources, Conservation and Recycling

698

414

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Highlights COVID-19 presents unprecedented challenge to all facets of human endeavour. A critical review of the negative and positive impacts of the pandemic is presented. The danger of relying on pandemic-driven benefits to achieving SDGs is highlighted. The pandemic and its interplay with circular economy (CE) approaches is examined. Sector-specific CE recommendations in a resilient post-COVID-19 world are outlined.

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Section: Opportunities For Circular Economy Post Covid-19mentioning

confidence: 99%

A critical analysis of the impacts of COVID-19 on the global economy and ecosystems and opportunities for circular economy strategies

Ibn‐Mohammed

Mustapha

Godsell

et al. 2021

Resources, Conservation and Recycling

698

414

View full text Add to dashboard Cite

show abstract

“…However, the necessary duration, frequency, and intensity of this distancing remains unclear in the presence of seasonality. To alleviate these problems, approaches to increase critical care capacity have included rapid construction or repurposing of hospital facilities and consideration of increased manufacturing and distribution of ventilators (8)(9)(10)(11).…”

Section: (Which Was Not Certified By Peer Review)mentioning

confidence: 99%

Social distancing strategies for curbing the COVID-19 epidemic

Kissler

Tedijanto

Lipsitch

et al. 2020

Preprint

264

355

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125 words). The SARS-CoV-2 pandemic is straining healthcare resources worldwide, prompting social distancing measures to reduce transmission intensity. The amount of social distancing needed to curb the SARS-CoV-2 epidemic in the context of seasonally varying transmission remains unclear. Using a mathematical model, we assessed that one-time interventions will be insufficient to maintain COVID-19 prevalence within the critical care capacity of the United States. Seasonal variation in transmission will facilitate epidemic control during the summer months but could lead to an intense resurgence in the autumn. Intermittent distancing measures can maintain control of the epidemic, but without other interventions, these measures may be necessary into 2022. Increasing critical care capacity could reduce the duration of the SARS-CoV-2 epidemic while ensuring that critically ill patients receive appropriate care.Full text. The COVID-19 pandemic is causing substantial mortality and a major strain on healthcare systems (1,2). With no pharmaceutical treatments available, interventions have focused on contact tracing, quarantine, and social distancing. Intensive testing, tracing, and isolation of cases has enabled control of transmission in some places, such as Singapore and Hong Kong (3). At the opposite extreme, many countries lack the testing and public health resources to mount similar responses to the COVID-19 epidemic, which could result in unhindered spread and catastrophic outbreaks. Between these responses, many countries are adopting measures termed "social distancing" or "physical distancing," closing schools and workplaces and limiting the sizes of gatherings. The goal of these strategies is to slow the spread of infection and reduce the intensity of the epidemic ("flatten the curve") (3), thus reducing risk of overwhelming health systems and buying time to develop treatments and vaccines. However, there is concern that such measures may have to stay in place over long . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. (which was not certified by peer review)

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“…To cope with this scenario, several strategies, including periodic screenings, weekly-shifts and other organizational measures are being implemented in a variety of settings to guarantee proper patient care. 9 Nonetheless, quantification and characterization of SARS-CoV-2 infection within health care facilities is unknown in most countries hard-hit by the COVID-19 epidemic. All rights reserved.…”

Section: Introductionmentioning

confidence: 99%

Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

García‐Basteiro

Moncunill

Tortajada

et al. 2020

Preprint

125

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Background: Health care workers (HCW) are a high-risk population to acquire SARS-CoV-2 infection from patients or other fellow HCW. At the same time, they can be contagious to highly vulnerable individuals seeking health care. This study aims at estimating the seroprevalence of antibodies against SARS-CoV-2 and associated factors in HCW from a large referral hospital in Barcelona, Spain, one of the countries hardest hit by COVID-19 in the world. Methods: From 28 March to 9 April 2020, we recruited a random sample of 578 HCW from the human resources database of Hospital Clinic in Barcelona. We collected a nasopharyngeal swab for direct SARS-CoV-2 detection through real time reverse-transcriptase polymerase chain reaction (rRT-PCR), as well as blood for plasma antibody quantification. IgM, IgG and IgA antibodies to the receptor-binding domain of the spike protein were measured by Luminex. The cumulative prevalence of infection (past or current) was defined by a positive SARS-CoV-2 rRT-PCR and/or antibody seropositivity. Results: Of the 578 total participants, 39 (6.7%, 95% CI: 4.8-9.1) had been previously diagnosed with COVID-19 by rRT-PCR, 14 (2.4%, 95% CI: 1.4-4.3) had a positive rRT-PCR at recruitment, and 54 (9.3%, 95% CI: 7.2-12.0) were seropositive for IgM and/or IgG and/or IgA against SARS-CoV-2. Of the 54 seropositive HCW, 21 (38.9%) had not been previously diagnosed with COVID-19, although 10 of them (47.6%) reported past COVID-19-compatible symptoms. The cumulative prevalence of SARS-CoV-2 infection was 11.2% (65/578, 95% CI: 8.9-14.1). Among those with evidence of past or current infection, 40.0% (26/65) had not been previously diagnosed with COVID-19, of which 46.2% (12/26) had history of COVID-19-compatible symptoms. The odds of being seropositive was higher in participants who reported any COVID-19 symptom (OR: 8.84, 95% CI: 4.41-17.73). IgM levels positively correlated with age (rho=0.36, p-value=0.031) and were higher in participants with more than 10 days since onset of symptoms (p-value=0.022), and IgA levels were higher in symptomatic than asymptomatic subjects (p-value=0.041). Conclusions: The seroprevalence of antibodies against SARS-CoV-2 among HCW was lower than expected. Thus, being a high-risk population, we anticipate these estimates to be an upper limit to the seroprevalence of the general population. Forty per cent of those with past or present infection had not been previously diagnosed with COVID-19, which calls for active periodic rRT-PCR testing among all HCW to minimize potential risk of hospital-acquired SARS-CoV-2 infections.

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Makeshift hospitals for COVID-19 patients: where health-care workers and patients need sufficient ventilation for more protection

Cited by 78 publications

References 1 publication

A critical analysis of the impacts of COVID-19 on the global economy and ecosystems and opportunities for circular economy strategies

A critical analysis of the impacts of COVID-19 on the global economy and ecosystems and opportunities for circular economy strategies

Social distancing strategies for curbing the COVID-19 epidemic

Seroprevalence of antibodies against SARS-CoV-2 among health care workers in a large Spanish reference hospital

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