Making Long-term Peritoneal Dialysis Possible

Nv, Dombros; Digenis, George E.; Dg, Oreopoulos

doi:10.1177/039139889702000301

Cited by 1 publication

(4 citation statements)

References 17 publications

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“…With respect to body size, the TWH patients were smaller than the general population-a finding that is in agreement with the reported characteristics of long-term survivors on PD (12) and that supports the role of adequate dialysis in long-term survival. Similarly, Abdel-Rahman's patients had mean body weight of 62.5 kg-a weight that was much lower than that of the short-term survivors (8).…”

Section: Discussionsupporting

confidence: 87%

“…In the full patient group under study (n = 36), 1 episode of peritonitis occurred every 52 months, a rate that is much lower than the usual peritonitis rate (12). Three of the 36 patients had no episodes of peritonitis.…”

Section: Discussionmentioning

confidence: 86%

“…Good family support is associated with good clinical outcomes in PD (12). None of the 10 TWH patients lived alone; all had supportive families who actively participated in the dialysis process.…”

Section: Discussionmentioning

confidence: 99%

“…The presence of comorbid conditions at the start of PD has an adverse influence on long-term outcome (12,14). Comorbid conditions also have an additive effect.…”

Section: Discussionmentioning

confidence: 99%

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Patients on Chronic Peritoneal Dialysis for Ten Years or More in North America

et al. 2000

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Thirty-six patients on peritoneal dialysis (PD) for more than ten years in six North American centers were analyzed retrospectively. In the six centers, the percentage of patients surviving for more than ten years varied between 0.8% and 7.3%. The study group included 27 females and 9 males aged 38.6 ± 14.2 years [mean ± standard deviation (SD)] at the start of treatment. Of the 36 patients, 28 were Caucasian. The most common cause of end-stage renal disease (ESRD), present in 12 patients, was chronic glomerulonephritis. Only 4 patients had diabetes. At the beginning of the study, 19 patients had hypertension (the most common comorbid condition); 11 had no comorbid conditions at the start. Creatinine clearance at the start was 4.12 ± 3.5 mL per minute, and the mean duration to anuria was 51 ± 25 months. Mean initial body weight was 55 ± 9 kg, and mean body surface area was 1.5 ± 0.2 m2. Serum albumin levels showed an increase from 33.8 ± 3.6 g/L at the start of the study to 38.2 ± 3.9 g/L at the end. Hospitalization rate was low at 0.5 ± 0.3 admissions per patient–year, and duration of hospitalization was 4.8 ± 3.7 days per patient–year. Peritonitis was the most common cause of hospitalization. The mean peritonitis rate was 1 episode every 52 ± 48 patient–months. There were 36 catheter changes in 18 patients; 16 patients had a single PD catheter throughout the period of study. Autonomous hyperparathyroidism was the most common long-term complication. At the end of the study period, 11 patients were still on PD, 9 had died, 5 had been transferred to hemodialysis (HD), 1 was alive with a functioning allograft, and 1 was lost to follow-up. We conclude that patients who survive longer than ten years on PD are most likely to be young Caucasian females, small in body size, who are non diabetic, with few comorbid conditions. These long-term survivors have few hospitalizations, and their peritonitis rate is low. In this group of patients, severe autonomous hyperparathyroidism is the most common long-term complication.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

“…The presence of comorbid conditions at the start of PD has an adverse influence on long-term outcome (12,14). Comorbid conditions also have an additive effect.…”

Section: Discussionmentioning

confidence: 99%

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