Malabsorption and artificial nutrition in patients with gut GvHD post allogenic stem cell transplantation: Home parenteral nutrition affects survival significantly

Purpose of review: This review discusses current practices regarding appropriate indications for parenteral nutrition (PN) in acutely ill hospitalized patients. We address specific indications for PN in the peri-operative period, and in inflammatory bowel disease, oncology, hepatobiliary, critical care and end-stage renal disease patients. Recent findings: Acutely ill hospitalized patients can develop intestinal failure requiring PN. Recent studies have provided insight into the main indications. The most common indications for inpatient PN include post-surgical complications, including prolonged ileus sepsis, fistula and leaks, and bowel obstruction, predominantly malignant. Severe or complicated inflammatory bowel disease and cancer treatment-related mucosal enteropathies (mucositis, enterocolitis, gut graft-versus-host disease) are the next commonest indications. Less frequent indications are primary motility disorders and inability to secure enteral access for enteral nutrition. Gastrointestinal failure of the intensive care patient is a separate entity resulting from multiple mechanisms, including an enteropathy and dysmotility. Summary: Despite the wider availability of nutrition support teams, use of PN is not without risk. The risks and benefits of PN in the acute setting need to be carefully considered even when it is indicated.

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When is parenteral nutrition indicated in the hospitalized, acutely ill patient?

Fragkos

Sebepos‐Rogers

Rahman

2020

Current Opinion in Gastroenterology

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Malabsorption and artificial nutrition in patients with gut GvHD post allogenic stem cell transplantation: Home parenteral nutrition affects survival significantly

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When is parenteral nutrition indicated in the hospitalized, acutely ill patient?

When is parenteral nutrition indicated in the hospitalized, acutely ill patient?

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