Malabsorption of iron as a cause of iron deficiencyanemia in postmenopausal women

Abstract

Objective:Malabsorption is one of the causes of iron deficiency anemia in postmenopausal women. The main objective of this study was to access the frequency of malabsorption in iron deficient anemic postmenopausal women.Methods:A total of 123 postmenopausal women were enrolled in the study. Of these 123 women, 50 were included as ‘control group’ and 73 patients with comparable severity of anemia were the ‘patient group’. Two tablets of ferrous sulfate (200 mg/tablet) along with one tablet of vitamin C (500 mg) were given to all participants. Serum iron levels were determined on samples collected from all participants before and after the administration of ferrous sulfate. Difference between before and after serum iron levels of normal and patients were compared.Results:No change in serum iron between sample one and sample two represented malabsorption. Out of 73, 5 postmenopausal anemic patients showed no change in their serum iron level after the administration of ferrous sulfate. This study shows that frequency of malabsorption of iron in postmenopausal women is 6.8%.Conclusion:Malabsorption should be considered as a prevalent cause of iron deficiency anemia in postmenopausal women. It should be properly diagnosed and iron response should be monitored properly in postmenopausal women with IDA after oral iron therapy. If a postmenopausal woman does not show any response to oral iron therapy, she should be evaluated for iron loss (blood loss and/or malabsorption). Intravenous route should be used for the administration of iron in these patients.

Wheat Fermentation With Enterococcus mundtii QAUSD01 and Wickerhamomyces anomalus QAUWA03 Consortia Induces Concurrent Gliadin and Phytic Acid Degradation and Inhibits Gliadin Toxicity in Caco-2 Monolayers

“…Iron deficiency is one of the prevailing nutrient deficiencies worldwide with reports of 800 million people suffering from this condition, particularly pregnant women and infants (McLean et al, 2009). High intake of phytic acid in cereal-based diets is one of the major risk factors for iron deficiency in developing countries (Qamar et al, 2015), which are more vulnerable to iron deficiency. For example, approximately 50% of non-pregnant women in Pakistan have been indicated to be iron deficient (Ullah et al, 2016).…”

Case Report: Complicated Meckel Diverticulum Spectrum in Children

“…Accordingly, we decided to perform an exploratory laparotomy for this case. In addition, the persistence of anemia after resection of MD might be the consequence of previous ileal atresia (16) or intestinal malabsorption (17).…”

Comparison of Serum Iron, Zinc, and Selenium Levels in Premenopausal and Postmenopausal Women in Ekpoma, Nigeria: A Descriptive Study

“…As mentioned, Fe is crucial in the transport of oxygen between tissues as well as in the transfer of electron in electron transport chain and in the regulation of cell growth and differentiation. In addition, it functions as a facilitator in free radical generation (11). Imbalance in cellular Fe level has been reported to cause serious health concerns.…”