Maladie de Kawasaki de l’adulte

Sève, P.; Jc, Lega

doi:10.1016/j.revmed.2010.04.006

Cited by 25 publications

(16 citation statements)

References 97 publications

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“…Since the disease is not common in adults, especially in Europe, it is very often misdiagnosed [ 1 - 4 ]. According to a review in 2011, 91 cases of adult KD had been described until that time [ 5 ]. Eight more cases have been added to the medical literature since then [ 6 - 13 ].…”

Section: Introductionmentioning

confidence: 99%

“…KD diagnosis is absolutely clinical since no specific diagnostic tests are available [ 5 ], although the proteins meprin A and filamin C were recently shown to possess potential as KD biomarkers [ 24 ]. The diagnosis is possible if an individual has persistent fever for more than 5 days, is unresponsive to broad-spectrum antibiotics, has no proof of infection and four out of the five following criteria: i) polymorphous rash; ii) conjunctivitis; iii) cervical lymphadenopathy; iv) oral changes including injected pharynx or lips, cracked or fissured lips, strawberry tongue; v) extremity changes starting with oedema or erythema and then progressing to desquamation of feet and hands, starting periungually [ 1 , 2 , 12 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…The diagnosis is possible if an individual has persistent fever for more than 5 days, is unresponsive to broad-spectrum antibiotics, has no proof of infection and four out of the five following criteria: i) polymorphous rash; ii) conjunctivitis; iii) cervical lymphadenopathy; iv) oral changes including injected pharynx or lips, cracked or fissured lips, strawberry tongue; v) extremity changes starting with oedema or erythema and then progressing to desquamation of feet and hands, starting periungually [ 1 , 2 , 12 , 15 ]. Unfortunately, these diagnostic criteria are valid for the diagnosis of KD in children, but have not yet been validated in adults [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

“…Coronary artery aneurysms (CAA) can change with time: they may regress, stay unchanged, progress to obstruction and, rarely, rupture or expand [ 3 ]. If coronary abnormalities are present, the diagnosis of KD can be set even when less than four of the aforementioned criteria are met [ 5 , 27 ]. Susceptibility to coronary artery lesions formation has been associated in various populations with specific single nucleotide polymorphisms in a wide range of genes, such as ITPKC [ 19 ], IL-10 [ 28 ], TGFBR2 [ 29 ], DC-SIGN [ 30 ] and KCNN2 [ 31 ].…”

Section: Introductionmentioning

confidence: 99%

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Adult Kawasaki disease in a European patient: a case report and review of the literature

et al. 2015

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IntroductionKawasaki disease is an acute necrotising vasculitis of the medium- and small-sized vessels, occurring mainly in Japanese and Korean babies and children, aged 6 months to 5 years. Its main complication is damage of coronary arteries, which has the potential to be fatal. Here we report a rare case of Kawasaki disease that occurred in a 20-year-old Greek adult.Case presentationA 20-year-old Greek man presented with high fever, appetite loss, nausea and vomiting, headache and significant malaise. He had an erythema of the palms and strikingly red lips and conjunctiva. As he did not respond to broad-spectrum antibiotics and after having excluded other possible diagnoses, the diagnosis of Kawasaki disease was set. He was treated with intravenous immunoglobulin and oral aspirin on the 10th day since the onset of the illness. His clinico-laboratory response was excellent and no coronary artery aneurysms were detected in coronary artery computed tomography performed 1 month later.ConclusionsThis report of an adult case of European Kawasaki disease may be of benefit to physicians of various specialties, including primary care doctors, hospital internists, intensivists and cardiologists. It demonstrates that a case of prolonged fever, unresponsive to antibiotics, in the absence of other diagnoses may be an incident of Kawasaki disease. It is worth stressing that such a diagnosis should be considered, even if the patient is adult and not of Asian lineage.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Adult Kawasaki disease in a European patient: a case report and review of the literature

et al. 2015

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“…• changes in lips and oral mucosa: cracked lips, strawberry tongue, oral and pharyngeal hyperemia; • cervical lymphadenopathy [4].…”

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confidence: 99%

A 19-year-old woman with polyarthritis, anterior uveitis and coronary vasculitis: A case of adult Kawasaki disease

D’Angelo

Varisco

et al. 2015

Joint Bone Spine

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Revisión de la enfermedad de Kawasaki en México, desde la perspectiva de las publicaciones médicas (enero de 1977 a mayo de 2012)

Sotelo-Cruz

2013

Archivos de Cardiología de México

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Kawasaki disease was described in 1967 by Tomisu Kawasaki. It affects children aged between one and 5 years, and it evolves with fever and small vessel vasculitis, which leads to cardiovascular complications, including coronary aneurisms, myocarditis, valve injuries, pericardial effusion and myocardial infarction; eventually involving many others organs. The etiology actually is not well known, as the exactly pathogenic mechanisms; however, now there are important advances. If the clinical signs and symptoms are identify early and the children received treatment with aspirin and intravenous immunoglobulin, the patients evolves without sequels. The Kawasaki disease is an infrequent disease in Mexico.

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Maladie de Kawasaki de l’adulte

Cited by 25 publications

References 97 publications

Adult Kawasaki disease in a European patient: a case report and review of the literature

Adult Kawasaki disease in a European patient: a case report and review of the literature

A 19-year-old woman with polyarthritis, anterior uveitis and coronary vasculitis: A case of adult Kawasaki disease

Revisión de la enfermedad de Kawasaki en México, desde la perspectiva de las publicaciones médicas (enero de 1977 a mayo de 2012)

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