Malakoplakia and adenocarcinoma of the caecum: a rare association.

Abstract

Colonic malakoplakia can occur either as a part of systemic disease with multiple colonic and extracolonic deposits or as an incidental finding associated with a rectal or sigmoidal adenocarcinoma.A case is reported which shows an association between malakoplakia and adenocarcinoma of the caecum.

Malakoplakia of Bone

“…9 Malakoplakia has been reported to occur in association with various tumors, like lymphoma and carcinoma, as well as nontumor conditions, including malnutrition, immunosuppression, tuberculosis, sarcoidosis and AIDS. 7,12 Our patient was malnourished, with protein energy malnutrition grade III.…”

CT of colonic malakoplakia in a patient with AIDS.

“…Colonic malakoplakia can occur as either a primary finding or an associ ated finding in patients with colonic carcinoma [4,5]. The lesions may involve the colon seg mentally or diffusely and can presentas a sin gle large mass,as multiple small lesions,or as a single small mass.…”

Malakoplakie des Kolons

“…Auch bei den bisher publizierten Fallberichten, in denen eine Malakoplakie des Kolons bestand, wurde vermehrt das Vorkommen weiterer Grunderkrankungen -u. a. kolorektale Tumoren [2,11,13], maligne hämatolo-gische Neoplasien [15], Neurofibromatose [15], Miliartuberkulose [15], Colitis ulcerosa [8], Heroinsucht [15] und Immundefekte [4,9] -beschrieben. Dieses Spektrum läßt sich durch die vorliegende Kasuistik erweitern, in der ein langjähriger Alkoholabusus mit sonographischem Nachweis einer Fettleber und laborchemischen Nachweis einer Transaminasenerhöhung bestand.…”