Malaria Parasitaemia and Variations in Haematological Parameters among Pregnant Women in Buea

Nyanga, Judith Lum Ndamukong; Wolloh, Gisele Christiana Miangu; Yunga, Nyanga Bernard; Jacqueline, Nchangsen; Ndamukong, Ngum

doi:10.9734/ijpr/2020/v4i330112

Cited by 2 publications

(1 citation statement)

References 14 publications

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“…In another hospital-based cross-sectional study in a region of Ghana, red cell and platelet counts were signi cantly lower in malaria than non-malaria infected patients (14). Ndamukong-Nyanga et al noted similar ndings in another cross-sectional study in Buea, Cameroon (22). They noted thrombocytopenia and anaemia to be the most signi cant predictors of malaria in their study region and concluded that these parameters could improve malaria diagnosis when utilised in conjunction with other clinical features.…”

Section: Discussionmentioning

confidence: 68%

Pancytopenia with severe thrombocytopenia in asymptomatic malaria in advanced pregnancy: a case report

Murewanhema

Musiniwa

Chimhina

et al. 2020

Preprint

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Background Malaria in pregnancy is associated with significant morbidity and mortality, and requires early diagnosis and intervention. Plasmodium falciparum is responsible for 98% of malaria cases in Zimbabwe and causes the most severe disease. Abnormal haematological parameters are a frequent finding in patients with malaria; however, they are rarely the sole presenting feature. Case presentation We present the case of a 32-year-old woman in her fifth pregnancy, with a history of one previous caesarean section, who presented for caesarean section and was incidentally noted to have severe thrombocytopenia. Subsequent investigations at a tertiary institution revealed a pancytopenia with thrombocytopenia as the most prominent feature in an asymptomatic patient. The unavoidable caesarean section done under platelet cover was eventful, with severe intractable haemorrhage necessitating an emergency hysterectomy. However, the patient made a full recovery with antimalarial treatment and blood product transfusions. Conclusion This case is presented to illustrate the need to consider malaria as a differential diagnosis in pregnant patients from malaria-transmitting areas who have thrombocytopenia. Previous studies have shown that thrombocytopenia can be a predictor of malaria in patients who present with fever, and a marker of disease severity, but has no utility in prognostication and follow-up.

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Section: Discussionmentioning

confidence: 68%

Pancytopenia with severe thrombocytopenia in asymptomatic malaria in advanced pregnancy: a case report

Murewanhema

Musiniwa

Chimhina

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

Prevalence of malaria parasite and its effects on some hematological parameters amongst pregnant women in Yola, Nigeria

Emmanuel,

Chessed,

Erukainure

et al. 2023

J.Umm Al-Qura Univ. Appll. Sci.

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Background Malaria infection during pregnancy presents a substantial health threat, adversely impacting both the mother and fetus. Its pathogenesis and clinical consequences further complicate diagnosis, treatment, and prevention, particularly in endemic regions. The precise impact of malaria infection on hematological profiles needs to be clearly elucidated, and the occurrence of malaria in expectant mothers still needs to be explored. Consequently, this study aims to assess the prevalence of malaria infection among pregnant women as well as to investigate and correlate the effects of this infection on the hematological parameters of pregnant women in Yola, Nigeria. Methods A structured hybrid questionnaire was used to gather socio-demographic, clinical, and obstetric data from 100 pregnant women aged 15–45 years. Malaria parasitemia was determined and confirmed using a light microscope, blood smear-staining techniques, and rapid diagnostic tests (RDT). At the same time, the packed cell volume (PCV) was measured using a microhematocrit reader. Also, the complete blood count was determined using Turk’s solution and Neubauer’s counting chamber (hemocytometer). Results Out of the 100 participants in the study, 76 tested positive for malaria, resulting in a prevalence rate of 76%. The age group between 30 and 34 years and multigravida recorded high values of malaria-infected women, accounting for 18 (23.7%) and 49%, respectively. Also, the study’s findings indicate that malaria-infected pregnant women had a significantly higher occurrence of anemia than those not infected (P = .045). In addition, eosinophil counts, total white blood cells (WBC), and neutrophil count were notably higher in pregnant women infected by malaria compared to those not infected (P < .05). Conversely, lymphocyte count, basophil count, and monocyte count were significantly lower in pregnant women infected by malaria compared to uninfected pregnant women. Conclusion Pregnant women participating in prenatal care at the Specialist Hospital in Yola, Nigeria, exhibited a relatively high occurrence of malaria parasite infection, and these infected pregnant women displayed a notable change in specific hematological parameters. The findings of this study offer valuable insights into the pathogenesis of malaria during pregnancy and contribute to improved diagnostic and management strategies for pregnant women at risk of malaria infection.

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Malaria Parasitaemia and Variations in Haematological Parameters among Pregnant Women in Buea

Cited by 2 publications

References 14 publications

Pancytopenia with severe thrombocytopenia in asymptomatic malaria in advanced pregnancy: a case report

Pancytopenia with severe thrombocytopenia in asymptomatic malaria in advanced pregnancy: a case report

Prevalence of malaria parasite and its effects on some hematological parameters amongst pregnant women in Yola, Nigeria

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