2007
DOI: 10.1016/j.ijgo.2007.03.054
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Malaria susceptibility and cortisol levels in pregnant women of eastern Sudan

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Cited by 7 publications
(2 citation statements)
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“…Malaria patients infected with P. vivax and P. falciparum have been found to present increased levels of blood cortisol (van Zon et al, 1982;Dekker et al, 1997;Davis et al, 1997;van Thien et al, 2001;Wilson et al, 2001;Blumer et al, 2005;Muehlenbein et al, 2005). Moreover, elevated cortisol levels were also reported in P. falciparum-infected patients with cerebral malaria (Blumer et al, 2005), while other studies correlated cortisol levels with increased parasitemia in pregnant women (Vleugels et al, 1989;Bouyou-Akotet et al, 2004Adam et al, 2007). Studies in murine models of malaria showed that an elevation in corticosterone levels upon infection correlated with increased parasitemia (Barthelemy et al, 2004) and disease severity (Van Zon et al, 1983).…”
Section: Discussionmentioning
confidence: 98%
“…Malaria patients infected with P. vivax and P. falciparum have been found to present increased levels of blood cortisol (van Zon et al, 1982;Dekker et al, 1997;Davis et al, 1997;van Thien et al, 2001;Wilson et al, 2001;Blumer et al, 2005;Muehlenbein et al, 2005). Moreover, elevated cortisol levels were also reported in P. falciparum-infected patients with cerebral malaria (Blumer et al, 2005), while other studies correlated cortisol levels with increased parasitemia in pregnant women (Vleugels et al, 1989;Bouyou-Akotet et al, 2004Adam et al, 2007). Studies in murine models of malaria showed that an elevation in corticosterone levels upon infection correlated with increased parasitemia (Barthelemy et al, 2004) and disease severity (Van Zon et al, 1983).…”
Section: Discussionmentioning
confidence: 98%
“…Another interesting feature described in the literature includes cortisolemia leading to loss of immunity in pregnant women infected with falciparum malaria. In this study Adam et al investigated 50 consecutive women with uncomplicated falciparum malaria and observed a positive correlation between cortisol levels and parasite count ( r = 0.332, P = 0.02) [ 10 ]. In our patient, there was no evidence of either primary or secondary adrenal insufficiency depicted by normal fasting morning cortisol of 15.5 mcg/dL and normal blood pressure throughout his hospital stay.…”
Section: Discussionmentioning
confidence: 99%