The Republic of South Sudan has experienced chronic food insecurity for decades and particularly in the last five years. This chronic food insecurity is a result of a combination of factors, including protracted conflicts, socio-economic fragility, lack of infrastructure, climate change and conflicts and wars in Sudan, Ukraine and the Middle East. In response, the South Sudan Government, UN agencies and international and national non-governmental actors have adopted measures to deal with the ongoing humanitarian crisis. Investing in the agricultural sector may offer a sustainable route to potentially alleviate the chronic food insecurity crisis. This brief describes the scale of the food insecurity facing populations in South Sudan. It also analyses the causes of food insecurity, responses by government and non-government actors and partners, and offers considerations for these actors to support ending food insecurity, especially via bolstering agriculture and livelihoods. This brief draws on published texts, grey literature (especially government and non-governmental organisation reports), print and online media releases, and discussions with politicians and civil servants from institutions that focus on food insecurity in South Sudan.