1973
DOI: 10.1530/acta.0.0730396
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Male Hermaphrodite With 46,xx Chromosome Constitution

Abstract: A 25-year-old male hermaphrodite with the sex chromosome constitution of 46,XX is reported. Clinical, endocrinological, pathological and cytogenetical studies are presented and discussed in comparison with findings in the so-called XX males reported in the literature. Some theories to explain the paradoxical occurrence of a testis in XX males and XX male hermaphrodites are mentioned and a possible aetiological relationship between these XX male syndromes and Klinefelter's syndrome is suggested.

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Cited by 7 publications
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“…On the other hand, XX males with genital abnormalities have been reported mainly in pediatric patients (Roe and Alfi 1977;Takayasu et al 1973;Shah et al 1961;Schweikert et al 1982;Cleveland and Chang 1965), and these cases seem clinically close to true hermaphroditism. Indeed, it has been very difficult to draw a clear line between these two conditions in our patients.…”
Section: Discussionmentioning
confidence: 99%
“…On the other hand, XX males with genital abnormalities have been reported mainly in pediatric patients (Roe and Alfi 1977;Takayasu et al 1973;Shah et al 1961;Schweikert et al 1982;Cleveland and Chang 1965), and these cases seem clinically close to true hermaphroditism. Indeed, it has been very difficult to draw a clear line between these two conditions in our patients.…”
Section: Discussionmentioning
confidence: 99%
“…The dermatoglyphic patterns in our patient were compatible with those in Klinefelter's syndrome, in that the total ridge count was much lower than those in normal male and female controls (Nanko 1975). We consider that XX males are etiologically analogous to patients with Klinefelter's syndrome (Takayasu et al 1973).…”
Section: Discussionmentioning
confidence: 99%