Malignancies Possibly Secondary to Anticancer Therapy

Belpomme, D; Carde, Patrice; Oldham, Robert K.; Mathé, G; Jacquillat, C; Chelloul, N; Weil, M; Auclerc, G.; C, Weisgerber; Tänzer, Thorsten; Bernard, J

doi:10.1007/978-3-642-80848-7_19

Cited by 17 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The latter patient also had cancer of the ovary. In a retrospective review in two cancer centers in Paris, 28 cases of dual malignancy were found [27] . Three of these patients had breast cancer and developed acute myelocytic leukemia after intensive (two cases) or mild (one case) chemotherapy and/or radiotherapy.…”

mentioning

confidence: 99%

Breast cancer and acute leukemia: Report of 24 cases and review of the literature

1978

View full text Add to dashboard Cite

Twenty-four cases of breast cancer and acute leukemia and three cases o f breast cancer and chronic myelocytic leukemia are reported. An additional 54 cases of acute leukemia and 13 cases of chronic myelocytic leukemia associated with breast cancer from the literature are reviewed.The mean interval between the diagnosis of breast cancer and the occurrence of acute leukemia is 6.9 years. In eight patients, the two diseases occurred simultaneously or within one year of each other. Four patients had acute lymphoblastic leukemia; the remainder had acute myelocytic leukemia or one of its variants.Seven patients received no postmastectomy radiotherapy or chemotherapy and the occurrence of acute leukemia between 1 and 23 years later cannot, therefore, be attributed t o the therapy given for the breast cancer. Forty-one patients received postoperative radiotherapy t o the mastectomy site. Combination chemotherapy was administered t o eight patients, five of whom were also treated with radiotherapy.Acute leukemia is estimated t o occur in patients treated for breast cancer with a sevenfold increased frequency over the expected number. This may be due to an increased risk of a second neoplasm in patients with a primary tumor; alterqatively, the qcute leukemia may be related t o the radiotherapy and/or cheqptherapy administered t o treat the breast cancer. Late death from leukemia after chemotherapeutic or radiotherapeutic remission of metastatic breast cancer is preferable t o morbidity and/or early death from inadequately treated breast cancef,

show abstract

mentioning

confidence: 99%

Breast cancer and acute leukemia: Report of 24 cases and review of the literature

1978

View full text Add to dashboard Cite

show abstract

“…However, the interval of 4 years between irradiation and the appearance of the second tumor seems too short, since the manifestation of radiation-induced solid tumors less than 10 years after radiotherapy is uncommon (Li et al, 1975). On the other hand, the combination of radiotherapy with chemotherapy may shorten the latent period (Belpomme et al, 1974). Although actinomycin D may be a mutagen due to its mode of action, its oncogenicity has not been proven.…”

Section: Radio-and Chemotherapymentioning

confidence: 98%

Wilms' tumor and adrenocortical carcinoma with hemihypertrophy and hamartomas

et al. 1978

View full text Add to dashboard Cite

A girl with hemihypertrophy and hamartomas, now 14 years old, had Wilms' tumor and subsequently developed adrenocortical carcinoma. The occurrence of the two tumors with the signs of an inborn defect of growth control supports the hypothesis that both tumors can be caused by the same etiologic factors, which are also teratogenic. An alternative explanation of induction of the second tumor by previous radio- and chemotherapy is discussed. Possible relationships between our case and the syndrome of Wiedemann and Beckwith are pointed out.

show abstract

Sézary Syndrome After Successful Treatment of Hodgkin's Disease

Büchner¹

1981

Arch Dermatol

View full text Add to dashboard Cite

Malignancies Possibly Secondary to Anticancer Therapy

Cited by 17 publications

References 18 publications

Breast cancer and acute leukemia: Report of 24 cases and review of the literature

Breast cancer and acute leukemia: Report of 24 cases and review of the literature

Wilms' tumor and adrenocortical carcinoma with hemihypertrophy and hamartomas

Sézary Syndrome After Successful Treatment of Hodgkin's Disease

Contact Info

Product

Resources

About