Malignancy Prevalence in the Dialyzed Population and in Waitlisted Potential Kidney Transplant Recipients

Pyrża, Michał; Głogowski, Tomasz; Wieliczko, Monika; Żebrowski, Paweł; Wojtaszek, Ewa; Semeniuk-Wojtaś, Aleksandra; Stec, Rafał; Nazarewski, Sławomir; Małyszko, Jolanta

doi:10.1016/j.transproceed.2022.01.025

Cited by 1 publication

(1 citation statement)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hemodialysis patients have an increased risk of malignancy due to impaired immune system function, malnutrition, immunosuppressants or cytotoxic drugs and other factors. 17,18 In our study, malignancy appear to be more likely to occur in patients with fracture, for reasons that are not clear. One possible reason for this is that the patient had inadvertently suffered a pathological fracture before the diagnosis of malignancy was made.…”

Section: Discussionmentioning

confidence: 54%

The Relationship Between Fracture and Mortality in a Chinese Maintenance Hemodialysis Patients Cohort

Liu,

Niu

et al. 2024

JMDH

View full text Add to dashboard Cite

Background Patients on maintenance hemodialysis have an increased risk of fracture. However, the relationship between fracture and poor prognosis is not clear. Methods A total of 182 maintenance hemodialysis patients were enrolled in the study. The relationship between fracture and poor prognosis (cardiovascular events, stroke, malignancy and 5-year all-cause mortality) were analyzed. Results 21 of 182 patients had a history of fracture at the time of enrollment. 26 patients had a new fracture after enrollment. A total of 57 fractures occurred in 47 patients, the most common fracture site was the rib. Patients with fracture group had a higher proportion of elderly and female, higher serum phosphorus and B-type natriuretic peptide and lower hemoglobin, albumin, and potassium compared with those without fracture. Age ( OR=3.809, 95% CI: 1.064–8.966, p=0.038 ), hemoglobin ( OR=0.961, 95% CI: 0.925–0.997, p=0.035 ), and serum phosphorus ( OR=3.325, 95% CI:1.104–10.019, p=0.033 ) were the independent risk factors of new fractures in MHD patients. The incidence of malignancy and 5-year all-cause mortality in patients with fracture was higher than those without fracture ( p<0.05 ). But there was no significant difference in the incidence of acute myocardial infarction or stroke. Conclusion 25.8% of maintenance hemodialysis patients had at least one fracture, with rib fractures accounting for the highest proportion. Age, hemoglobin and serum phosphorus were the independent risk factors of new fractures. The incidence of malignancy and 5-year all-cause mortality in patients with fracture was higher than those without fracture, but there was no significant difference in the incidence of acute myocardial infarction and stroke.

show abstract

Section: Discussionmentioning

confidence: 54%