Malignant atrophic papulosis (Degos’ disease) involving three generations of a family

Degos’ Disease: A Case with Cutaneous Lesions Only: Absence of Paramyxovirus by PCR

“…The prognosis is worse for men [9]. Our patient has survived for 3 years without any visceral complications.…”

“…According to some authors [3,8,9], Degos' disease can be classified into two varieties: a systemic malignant form with visceral involvement and a poor prognosis, and a cutaneous benign form without visceral involvement and a good prognosis. The prognosis is worse for men [9].…”

Diffuse atrophic papules and plaques, intermittent abdominal pain, paresthesias, and cardiac abnormalities in a 55-year-old woman

“…1,2 Although the etiology of MAP is unclear, theories have implicated a viral pathogenesis, autoimmune dysfunction, and, more recently, dysregulation of interferon-α signaling and complement activation as mediators of endothelial damage. 3,4 MAP is most often diagnosed in young to middle-aged Caucasian adults but may affect individuals of all ages and races.…”

Malignant Atrophic Papulosis with Severe Gastrointestinal Perforation and Omental Necrosis: A Case Report

“…Some studies have indicated a familial trend. 8,9 The systemic nature of MAP means that multiple organs can be involved, including the skin which seems to be the onset system and presents in almost all patients, gastrointestinal tract, nervous system, lung, myocardium and adrenal gland. 1 Skin lesions are distinctive, typically scattered on the trunk and extremities, with the face, soles of the feet, scalp and palms of the hands seldom involved.…”