Malignant Cervical Schwannoma: An Unusual Pelvic Tumor

Lallas, Thomas A.; Mehaffey, Philip; Lager, Donna J.; Voorhis, Bradley J. Van; Sorosky, Joel I.

doi:10.1006/gyno.1998.5234

Cited by 24 publications

(9 citation statements)

References 2 publications

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“…They have a good prognosis if complete surgical resection is achieved, otherwise they tend to relapse (Borghese et al, 2002). Cases of malignant schwannomas of the cervix report disease-free survival of up to 10 years with hysterectomy (Lallas et al, 1999). On the other hand, cervical leiomyomas are very uncommon and are estimated to represent 0.6% in hysterectomy specimens.…”

Section: Discussionmentioning

confidence: 99%

Surgical management of a large neurilemmoma-like leiomyoma of the uterine cervix mimicking a retroperitoneal tumor

Morales

Suescún

Martínez

et al. 2017

Gynecologic Oncology Reports

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Section: Discussionmentioning

confidence: 99%

Surgical management of a large neurilemmoma-like leiomyoma of the uterine cervix mimicking a retroperitoneal tumor

Morales

Suescún

Martínez

et al. 2017

Gynecologic Oncology Reports

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“…An additional case of a retroperitoneal schwannoma localized in the pelvic cavity with complete cystic degeneration, mimicking an ovarian carcinoma, was reported14 as well as one presacral neurilemoma 15. One pelvic retroperitoneal neurilemoma arose in the fallopian tube,16 and one malignant schwannoma arose in the cervix 17. Yadav et al reported one case of neurilemoma located in the right adnexum,18 and Sinha et al reported two cases of pelvic schwannomas located in the broad ligament, with the clinical expression of a broad ligament myoma 9.…”

Section: Resultsmentioning

confidence: 95%

Pelvic schwannoma in the right parametrium

Machairiotis¹,

Stylianaki²,

Karatrasoglou³

et al. 2013

IJGM

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Neurilemomas are benign usually encapsulated nerve sheath tumors derived from the Schwann cells. These tumors commonly arise from the cranial nerves as acoustic neurinomas but they are extremely rare in the pelvis and the retroperitoneal area (less than 0.5% of reported cases), unless they are combined with von Recklinghausen disease (type 1 neurofibromatosis). We report the case of a 58-year-old female with pelvic schwannoma, 6.5 × 5.5 cm in size, in the right parametrium. This is the first case reported in the literature. Based on the rarity of this tumor and in order to ensure optimum treatment and survival for our patient, we performed laparotomy with total abdominal hysterectomy and en-block tumor excision. A frozen section was taken during the surgery before complete resection of the mass, which was ambiguous. Because of the possibility of malignancy, complete excision of the mass was performed, with pelvic blunt dissection. Histological examination showed a benign neoplasm, originating from the cells of peripheral nerve sheaths; diagnosis was a schwannoma. There were degenerative areas, including cystic degeneration, hemorrhagic infiltrations, ischemic foci with pycnotic cells, and collagen replacement. Pelvic schwannomas are rare neoplasms that can be misdiagnosed. Laparoscopy is a safe and efficient option for approaching benign pelvic tumors and might offer the advantage of better visualization of structures due to the magnification in laparoscopic view, especially in narrow anatomic spaces.

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“…[15] One pelvic retroperitoneal neurilemoma arose in the fallopian tube, [16] and one malignant schwannoma arose in the cervix. [17] Yadav et al [18] reported one case of neurilemoma located in the right adnexa, and Sinha et al [9] reported two cases of pelvic schwannomas located in the broad ligament, with the clinical expression of a broadligament myoma. One reported case of neurilemoma of the pelvis mimicked a myoma of the uterus.…”

Section: Discussionmentioning

confidence: 99%