Malignant Fibrous Histiocytoma and Squamous Carcinoma Derived from a Burn Scar

Abstract

Malignant fibrous histiocytoma is the most common type of soft tissue sarcoma in late adult life. The tumour may be seen rarely in burn scars and accompanying other kinds of malignancies. We herein report a case of a tumour that derived from an old burn scar on the scalp. The histological examination revealed that the tumour contained both malignant fibrous histiocytoma and squamous carcinoma areas. Malignant transformation in a burn scar is a well-known development; therefore, a new lesion occurring within the scar should not be neglected.

Undifferentiated Pleomorphic Sarcoma of a Chronic Burn Scar of the Knee With Lymph Node Metastasis

“…Current workup and treatment of burn scar UPS should not differ from sporadic UPS. The majority of the few cases of previously reported burn scar UPS have been localized lesions as seen in Table 1, save for the patient reported here and the one case reported by Yamamura et al 6,26–34 As mentioned above, because distinguishing between indolent and aggressive forms of UPS is difficult at the present, it might just be that the two cases developed aggressive forms of UPS during the latent period since burn injury. One may speculate that the longer the duration between burn and diagnosis, the higher possibility of metastasis, but based on the cases seen in Table 1, there does not seem to be a correlation.…”

Marjolin’s Ulcer: Experience from a Developing Country

“…Considering these factors, surgeons in developing countries should be well versed with the management of burn and it's complications including MU. Marjoilin's ulcer is an uncommon but aggressive malignancy that develops in about 1-2% of burn scars and accounts for about 1% of all skin cancers [3,4]. In the majority of cases, the MU is a squamous cell carcinoma (SCC) but other histological types of skin malignancies have been described including basal cell carcinoma (BCC), melanoma and sarcomas.…”

Surgical Management of Invasive Atypical Fibroxanthomas/Undifferentiated Pleomorphic Sarcomas of the Scalp: A Systematic Review Comparing Outer Table Resection to Full-Thickness Craniectomy

“…A modified Mohs micrographic surgery (mMMS) approach with circumferential margin assessment may allow for maximal tissue sparing and reduce the risk of recurrence 3. These lesions, particularly UPS, are capable of infiltrating the underlying pericranium and calvarium 3–10. When this occurs, mMMS is not a feasible option for definitive management.…”